Results 31 to 40 of about 10,558,163 (239)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A Robust Watermarking Scheme in YCbCr Color Space Based on Channel Coding

IEEE Access, 2019
The rapid development of big data and cloud computing technologies greatly accelerate the spreading and utilization of images and videos. The copyright protection for images and videos is becoming increasingly serious.
Yun Tan, Jiaohua Qin, Xuyu Xiang, Wentao Ma, Wenyan Pan, Neal N. Xiong   +5 more
doaj   +1 more source

Development of a High-Density Genetic Map for Muscadine Grape Using a Mapping Population from Selfing of the Perfect-Flowered Vine ‘Dixie’

Plants, 2022
Intraspecific diversity of the immune grape Muscadinia rotundifolia Michaux. can serve as a rich source of valuable resistance loci to the most widespread pathogens and pests of grapevine.
Kirill Lytkin, Vasily Nosulchak, Magamedgusein Agakhanov, Elena Matveikina, Ekaterina Lushchay, Dmitry Karzhaev, Evgenii Raines, Irina Vasylyk, Nataliya Rybachenko, Elizaveta Grigoreva, Vladimir Volkov, Vladimir Volynkin, Laurent Gentzbittel, Elena Potokina   +13 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Influence of Image Processing and Layer-to-Background Contrast on the Reliability of Flatbed Scanner-Based Characterisation of Additively Manufactured Layer Contours

Applied Sciences, 2020
Flatbed scanners (FBSs) provide non-contact scanning capabilities that could be used for the on-machine verification of layer contours in additive manufacturing (AM) processes. Layer-wise contour deviation assessment could be critical for dimensional and
David Blanco, Pedro Fernández, Alejandro Fernández, Braulio J. Alvarez, José Carlos Rico   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Data-driven parameter optimization for bead geometry in wire arc additive manufacturing of 17-4 PH stainless steel

Journal of Advanced Joining Processes
Due to its high strength, corrosion resistance, and toughness, 17-4 Precipitation Hardening (PH) stainless steel is widely used in aerospace, petrochemical, and marine industries. Additive manufacturing (AM) technologies enable the fabrication of complex
Muhammad Irfan, Yun-Fei Fu, Shalini Singh, Sajid Ullah Butt, Abul Fazal Arif, Osezua Ibhadode, Ahmed Qureshi   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

AscentAM: A Software Tool for the Thermo-Mechanical Process Simulation of Form Deviations and Residual Stresses in Powder Bed Fusion of Metals Using a Laser Beam

Modelling
Due to the tool-less fabrication of parts and the high degree of geometric design freedom, additive manufacturing is experiencing increasing relevance for various industrial applications. In particular, the powder bed fusion of metals using a laser beam (
Dominik Goetz, Hannes Panzer, Daniel Wolf, Fabian Bayerlein, Josef Spachtholz, Michael F. Zaeh   +5 more
doaj   +1 more source