Results 121 to 130 of about 12,550,101 (310)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Comparison of experts in the non-additive case [PDF]
We adapt the model of comparisons of experts initiated by Lehrer («Comparison of experts JME 98») to a context of uncertainty which cannot be modelised by expected utility. We examine the robustness of Lehrer in this new context. Unlike expected utility,
Jean-Philippe Lefort
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Quantile Approach to Integration with Respect to Non-additive Measures [PDF]
, 2012 The aim of this paper is to introduce some classes of aggregation functionals when the evaluation scale is a complete lattice. We focus on the notion of quantile of a lattice-valued function which have several properties of its real-valued counterpart and we study a class of aggregation functionals that generalizes Sugeno integrals to the setting of
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Philosophical Foundation of Non-Additive Measure and Probability [PDF]
, 2018 In this paper, non-additivity of a set function is interpreted as a method to express relations between sets which are not modeled in a set theoretic way.
Maaß, Sebastian
core
On non-additive measures of inaccuracy [PDF]
Czechoslovak Mathematical Journal, 1976 Gupta, H. C., Sharma, Bhu Dev
openaire +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Autocontinuity and convergence theorems for the Choquet integral [PDF]
Our aim is to provide some convergence theorems for the Choquet integral with respect to various notions of convergence. For instance, the dominated convergence theorem for almost uniform convergence is related to autocontinuous set functions ...
Yann Rébillé
core