Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Association of preoperative systemic immune-inflammation index and geriatric nutritional risk index with prolonged postoperative length of stay in older patients with hip fracture: A retrospective cohort study. [PDF]
Medicine (Baltimore)Zhang J, Yu X, Sun D.
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Joint Association of Hydration Status and Sleep Quality with Type 2 Diabetes Mellitus in a Population-Based Study. [PDF]
NutrientsHan M +8 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Attitude toward information and learning under multiple priors [PDF]
This paper studies learning under multiple priors by characterizing the decision maker's attitude toward information. She is incredulous if she integrates new information with respect to only those measures that minimizes the likelihood of the new ...
André Lapied +2 more
core
Gestational age-dependent risk patterns in small for gestational age preterm infants: a large multivariable cohort study. [PDF]
Front PediatrFigueras-Aloy J +5 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Some Fubini theorems on product sigma-algebras for non-additive measures [PDF]
We give some Fubini's theorems (interversion of the order of integration and product capacities) in the framework of the Choquet integral for product sigma-algebras. Following Ghirardato this is performed by considering slice-comonotonic functions.
Jean-Philippe Lefort, Alain Chateauneuf
core
Assessment of a feed additive consisting of montmorillonite-illite mixed layer clay mineral (1g557) for all animal species for the renewal of its authorisation (FIM Biotech GmbH). [PDF]
EFSA JEFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +21 more
europepmc +1 more source