Results 271 to 280 of about 183,492 (354)

Association of cardiometabolic index with non-alcoholic fatty liver disease among Iranian adults of the amol cohort study. [PDF]

BMC Gastroenterol
Behzad C, Shateri Z, Motamed N, Maadi M, Ajdarkosh H, Sobhrakhshankhah E, Zamani F, Doustmohammadian A, Nouri M.   +8 more
europepmc   +1 more source

Correlation of serum aspartate aminotransferase level to platelet count ratio index with non-alcoholic fatty liver disease activity score

, 2019
Dulal Chandra Das, Shahinul Alam, Sheikh Mohammad Noor-E-Alam, Mohammed Kamal, Forhadul Hoque Mollah, Mamun-Al-Mahtab Mamun-Al-Mahtab   +5 more
openalex   +2 more sources

Bioorthogonal Chemistry in Biomolecule Quantification: A Review of Reactions and Strategies

Chemistry – A European Journal, EarlyView.
This review summarizes the application of catalyst‐free bioorthogonal reactions: Staudinger ligation, strain promoted azide alkyne cycloaddition, inverse electron‐demand Diels–Alder, and 2‐cyanobenzothiazole cysteine condensation in the semi‐quantitative and quantitative analysis of biomolecules.
Mingze Yang, Shiqi Wang
wiley   +1 more source

Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis. [PDF]

Front Nutr
Liu Q, Luan H, Duan Z, Ai J, Wang Y, Chen P.   +5 more
europepmc   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on, Cancer Antigen C15‐3, Biochemical and Histopathological Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Cancer Nexus, EarlyView.
ABSTRACT This work compares the effect of African walnut oil and docosahexaenoic acid (DHA) on cancer antigen C15‐3 (CA15‐3), biochemical, and histopathological markers of rats with 7,12‐dimethylbenz[a]anthracene‐induced (DMBA) breast cancer. 18 rats with tumor were randomized into three groups of six rats each: The negative control, the positive ...
Fabrice Tonfack Djikeng, Brenda Sandrine Tiadjo, Eurydice Flore Tiepma Ngongang, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

Mechanisms Linking Obesity with Non-Alcoholic Fatty Liver Disease (NAFLD) and Cardiovascular Diseases (CVDs)-The Role of Oxidative Stress. [PDF]

Curr Issues Mol Biol
Varra FN, Varras M, Varra VK, Theodosis-Nobelos P.   +3 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Bexicaserin in Healthy Participants: A First‐in‐Human Randomized, Double‐Blind, Placebo‐Controlled Single Ascending Dose Escalation Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective 5‐hydroxytryptamine 2C (5‐HT2C) superagonist in development for the treatment of seizures in developmental and epileptic encephalopathies (DEEs). This double‐blind, placebo‐controlled, single ascending dose (SAD) Phase 1 study aimed to assess the safety, tolerability, and pharmacokinetic (PK) and ...
Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R Srinivas, Randall Kaye   +6 more
wiley   +1 more source

Role of obesity and estrogen deficiency in non‑alcoholic fatty liver disease: Insights from a mouse model. [PDF]

Mol Med Rep
Afonso-Alí A, Dicroce-Giacobini J, Teixido-Trujillo S, Porrini E, Pérez-Pérez JA, García-Hernández S, Luis-Lima S, Abrante-Pérez B, Hernández-Bustabad A, Acosta-González NG, Iglesias-Hernández M, Díaz-Martín L, Rodríguez-González C, Hernández-Guerra M, Rodríguez-Rodríguez AE.   +14 more
europepmc   +1 more source

A multipart phase 1 study of the safety, pharmacodynamics and pharmacokinetics of ALG‐055009, a novel thyroid hormone receptor beta (THR‐β) agonist for metabolic dysfunction‐associated steatohepatitis (MASH), in healthy participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi, Benedetta Massetto, Megan Fitzgerald, Kha Le, Stanley Wang, Ifong Kan‐Eng, Meenakshi Venkatraman, Naqvi Mohammad, Lawrence Blatt, Tse‐I Lin, Sushmita M. Chanda, John Fry   +11 more
wiley   +1 more source

Exploring the role of gut microbiota in inflammatory bowel disease patients comorbid with non-alcoholic fatty liver disease. [PDF]

Gut Pathog
Hu J, Zhou C, Zhang L, Chen Y, Li J, Li J, Duan L.   +6 more
europepmc   +1 more source