Results 131 to 140 of about 10,125,713 (289)

Micro-Demand Systems Analysis of Non-Alcoholic Beverages in the United States: An Application of Econometric Techniques Dealing With Censoring [PDF]

A censored Almost Ideal Demand System (AIDS) and a Quadratic Almost Ideal Demand System (QUAIDS) were estimated in modeling non-alcoholic beverages. Five estimation techniques were used, including the conventional Iterated Seemingly Unrelated Regression (
Alviola, Pedro A., IV, Wu, Ximing, Capps, Oral, Jr.   +2 more
core  

Non-Alcoholic Steatohepatitis Patient Characterization and Real-World Management Approaches in Italy [PDF]

Elisabetta Bugianesi,1 Luca Miele,2,3 Giovanna Donnarumma,4 Katrine Grau,5 Mariarosaria Mancuso,4 Preethy Prasad,5 Andrea Leith,6 Victoria Higgins6 1Division of Gastroenterology, Department of Medical Sciences, University of Torino, AOU Città della ...
Miele L, Leith A, Grau K, Higgins V, Prasad P, Donnarumma G, Mancuso M, Bugianesi E   +7 more
core  

Thyroid-stimulating hormone variation within the euthyroid range and the severity of fatty liver disease in patients with type 2 diabetes mellitus: A cross-sectional study

Journal of the Pakistan Medical Association
Objective: To identify the relationship between thyroid-stimulating hormone levels within the euthyroid range and the severity of fatty liver disease in patients with type 2 diabetes mellitus.
Sunnia Khan, Asim Zulfiqar, Kiran Fatima, Samia Kausar, Muhammad Farooq, Qurrat ul Ain Kalim   +5 more
doaj   +1 more source

[Non alcoholic steatohepatitis].

Medicina, 1995
A prospective study of 21 patients with the diagnosis of non-alcoholic steatohepatitis (NASH) was carried out. All patients had hepatomegaly and in 10 (48%) image studies were consistent with steatosis and/or fibrosis. Biochemically, there was increase of AST, ALT and cholesterol in 48%, of GGT in 52% and of alkaline phosphatase in 38%.
E, Manero, J A, Findor, A, Avagnina, S, de Elizalde, B, Elsner   +4 more
openaire   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

DUCK‐Net: automated deep learning segmentation of ductular reactions in murine liver injury captures multicellular niche dynamics from H&E morphology

The Journal of Pathology, EarlyView.
Abstract Ductular reactions (DRs) are dynamic and complex multicellular responses that occur as a result of various hepatic injuries. Precise identification and quantification of the extent of DRs is a cornerstone of pre‐clinical modelling of liver disease, with links to inflammation, fibrosis, regeneration, and disease severity.
Nathalie Feeley, Kai Williams, Caitlin McCaffrey, Daniel Field, Kyle Davies, Hugh Warden, Luke Boulter, Steve Thorn, Tak Yung Man, Wei‐Yu Lu, Stephen J Wigmore, Ewen M Harrison, Stuart J Forbes, Ian P Tomlinson, Timothy J Kendall, Rachel V Guest   +15 more
wiley   +1 more source

Review article: is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions?

, 2012
Background Non-alcoholic fatty liver disease (NAFLD) is currently conceptualised as a clinical spectrum that results from a 'multiple-hit' process which begins with simple steatosis and subsequently renders the hepatocytes susceptible to a ...
Y. Yilmaz, YILMAZ, YUSUF
core   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source