Results 131 to 140 of about 53,092 (237)

Associations of Adiposity With Gut Microbiota Composition Among Adults—Results From a Federated Analysis of Individual Participant Data From Eight European Observational Studies

Obesity Reviews, EarlyView.
ABSTRACT Gut microbiota may contribute to the adiposity‐associated disease risk, but human studies reported inconsistent associations of adiposity with gut microbiota composition. We examined associations of body mass index (BMI) with alpha diversity and relative microbial abundance at the phylum and genus taxonomic levels (based on 16S rRNA amplicon ...
Carolina Schwedhelm, Mariona Pinart, Sofia K. Forslund‐Startceva, Kolade Oluwagbemigun, Andreas Dötsch, Kristina Schlicht, Florian Schwarz, Sofia M. Siampani, Demetris Avraam, Maria De Angelis, Jildau Bouwman, Patrizia Brigidi, Giovanna Caderni, Francesco Maria Calabrese, Rafael R. C. Cuadrat, Carlotta De Filippo, Francesca De Filippis, Danilo Ercolini, Marco Fabbrini, Matthias Laudes, Ute Nöthlings, Serdar Özsezen, Itai Sharon, Matthias B. Schulze, Silvia Turroni, Francesco Vitali, Tobias Pischon, Katharina Nimptsch   +27 more
wiley   +1 more source

Correction: Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice. [PDF]

Lipids Health Dis
Nan Y, Wang R, Zhao S, Han F, Wu WJ, Kong L, Fu N, Kong L, Yu J.   +8 more
europepmc   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Recent advances in non-alcoholic steatohepatitis-associated hepatocellular carcinoma: immune cells, metabolic dysregulation, and therapeutic strategies. [PDF]

Front Oncol
Liu L, Duan X, Ju B.
europepmc   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Insights into Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis: The Role of Fibrinogen and Pepsinogen. [PDF]

Middle East J Dig Dis
Eslami Z, Norouzi A.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

L-ascorbate prevents non-alcoholic steatohepatitis-based hepatocarcinogenesis in Sod1/Prdx4 double-knockout mice. [PDF]

Sci Rep
Osaki T, Homma T, Maeda Y, Yamada KI, Yokoyama C, Toyokuni S, Fujii J.   +6 more
europepmc   +1 more source

Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study.

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation. This study aimed to compare the efficacy of conventional EIS and EISL in treating esophageal varices and the usefulness of EISL.
Keita Maki, Hiroaki Haga, Kyoko Hoshikawa, Tomohiro Katsumi, Fumiya Suzuki, Fumi Uchiyama, Yoshiyuki Ueno   +6 more
wiley   +1 more source

Pathogenesis and Treatment of Non-alcoholic Steatohepatitis and Its Fibrosis: A Systematic Review. [PDF]

Cureus
Ahmed T, Farooq S, Naveed MA, Shahzad A, Rehman W, Haider T, Noor NN.   +6 more
europepmc   +1 more source