Results 41 to 50 of about 10,125,713 (289)

Rifaximin in Non-Alcoholic Steatohepatitis: An Open-Label Pilot Study [PDF]

, 2017
Aim Gut microbial dysbiosis is implicated in the pathogenesis of non-alcoholic steatohepatitis (NASH). We investigated downstream effects of gut microbiota modulation on markers of hepatic inflammation, steatosis, and hepatic and peripheral insulin ...
Atkinson, Stephen, Marchesi, Julian R, Julie Stove, Wai, Sann N., Yee, Michael S., Stove, Julie, Goldin, Robert D, Jackson, Nicola, Simon D. Taylor-Robinson, Wai, S.N., Quentin M. Anstee, Holmes, E., Cobbold, Jeremy F.L., Umpleby, A. Margot, Fitzpatrick, Julie, Yee, M.S., Thursz, Mark R., Shojaee-Moradie, Fariba, Fariba Shojaee-Moradie, Umpleby, A.M., Taylor-Robinson, S.D., Holmes, Elaine, Shojaee-Moradie, F., A. Margot Umpleby, Anstee, Quentin M, Thomas, E.L., Ann Smith, Bell, Jimmy D, Fitzpatrick, J., Taylor-Robinson, Simon D, Marchesi, Julian R., Bell, Jimmy D., Thursz, M.R., Goldin, R.D., Julian R. Marchesi, Nicola Jackson, Thursz, Mark R, Atkinson, S., Taylor-Robinson, Simon D., Mark R. Thursz, Anstee, Q.M., Wai, Sann N, Goldin, Robert D., Cobbold, Jeremy FL, Jackson, N.C., Marchesi, Julian Roberto, Julie Fitzpatrick, Smith, A., Thomas, E. Louise, Robert D. Goldin, Stove, J., Smith, Ann, Marchesi, J.R., Jeremy F.L. Cobbold, Umpleby, A Margot, Anstee, Quentin M., Elaine Holmes, Bell, J.D., Stephen Atkinson, Sann N. Wai, E. Louise Thomas, Michael S. Yee, Cobbold, J.F.L., Thomas, E Louise, Yee, Michael S, Jimmy D. Bell   +65 more
core   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Non-alcoholic Steatohepatitis

Medicine, 2002
Abstract The term ‘non-alcoholic steatohepatitis' (NASH) was introduced in 1980 to define a condition that is histologically similar to alcoholic liver disease but in which alcohol has no part and that is most commonly associated with obesity and/or type 2 diabetes. The condition can lead to cirrhosis and hepatocellular cancer.
H, Zantout, K, Barada
  +8 more sources

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

The db mouse as a model for steatohepatitis [PDF]

, 2006
Includes bibliographical references.Fatty liver disease is a collective phrase for a spectrum of diseases characterised by increased liver fat content.
Sutherland, Jason Robert
core   +1 more source

Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium

Hepatology Communications, EarlyView., 2022
Abstract Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retrospective cohort study of adult SLKT recipients between 2002 and 2017 at six centers in six United Network ...
Jennifer Jo, Gonzalo Crespo, Dyanna Gregory, Jasmine Sinha, Jiaheng Xie, Min Zhang, John Magee, Pranab Barman, Yuval A. Patel, Aaron Schluger, Kara Walters, Scott Biggins, Natalia Filipek, Giuseppe Cullaro, Randi Wong, Jennifer C. Lai, Gabriel J. Perreault, Elizabeth C. Verna, Pratima Sharma, Lisa B. VanWagner   +19 more
wiley   +1 more source

Paraoxonase Activity in Cirrhotic and Non Alcoholic Steatohepatitis Patients [PDF]

Catrina: The International Journal of Environmental Sciences, 2013
Paraoxonase-1 (PON1) is an esterase and lactonase synthesized by the liver and found in the circulation associated with high-density lipoproteins (HDL). The physiological function of PON1 seems to degrade specific oxidized cholesteryl esters and oxidized
Aziza Ismail, Mohy Abdelfattah, Mohamed Hassan, Fathallah Hassan   +3 more
doaj   +1 more source

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Clinical Management of Non-alcoholic Steatohepatitis and the Role of the Cardiologist

, 2023
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of fat-associated liver conditions that increase risk of cardiovascular disease and mortality. The diagnosis and clinical management of NAFLD remain a challenge for cardiologists.
Caballero-Valderrama, María de Regla, Barón-Esquivias, Gonzalo, Palacios Castelló Carlos, Millán-Rodríguez Carlos   +3 more
core   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source