Results 41 to 50 of about 53,092 (237)

Src kinase as a potential therapeutic target in non‐alcoholic and alcoholic steatohepatitis

open access: yesClinical and Translational Discovery, 2022
Non‐alcoholic steatohepatitis (NASH) and alcohol‐associated steatohepatitis (ASH) are the major cause of liver‐related mortality with limited therapeutic options available.
Dhadhang Wahyu Kurniawan   +13 more
doaj   +1 more source

Monozygotic twins with NASH cirrhosis: cumulative effect of multiple single nucleotide polymorphisms?

open access: yesAnnals of Hepatology, 2016
Multiple genetic and environmental factors interact to determine an individual’s predisposition to non-alcoholic fatty liver disease and its phenotypic characteristics. Association studies have found a number of alleles associated with the development of
Jane I. Grove   +4 more
doaj   +1 more source

Effect of quercetin on the clinical course of non-alcoholic steatohepatitis and diabetic kidney disease against comprehensive treatment of type 2 diabetes patients

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2020
Background. The purpose of the study was to determine the probable effect of a complex of metformin, rosuvastatin, essential phospholipids, and quercetin on the clinical course of non-alcoholic steatohepatitis, diabetic kidney disease, type 2 diabetes ...
O.S. Khukhlina   +2 more
doaj   +1 more source

Non alcoholic steatohepatitis.

open access: yesLe Journal medical libanais. The Lebanese medical journal, 2002
Abstract The term ‘non-alcoholic steatohepatitis' (NASH) was introduced in 1980 to define a condition that is histologically similar to alcoholic liver disease but in which alcohol has no part and that is most commonly associated with obesity and/or type 2 diabetes. The condition can lead to cirrhosis and hepatocellular cancer.
H, Zantout, K, Barada
  +8 more sources

Pathohistological characteristics of steatohepatitis on needle biopsy sample from 100 patients [PDF]

open access: yesMedicinski Podmladak, 2019
Introduction: Steatohepatitis is a form of fatty liver disease, in which there is a deposit of fat and steatosis which occurs in two forms: alcoholic and non-alcoholic fatty liver disease.
Milićević Anđela   +2 more
doaj  

Myosteatosis rather than sarcopenia associates with non‐alcoholic steatohepatitis in non‐alcoholic fatty liver disease preclinical models

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2021
Background Non‐alcoholic fatty liver (NAFL) disease (NAFLD) is the most common chronic liver disease in the world. While most subjects have ‘inert’ NAFL, a subset will progress to non‐alcoholic steatohepatitis (NASH) and its life‐threatening ...
Maxime Nachit   +7 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Evaluation of liver stiffness measurement–based scores in liver transplantation recipients

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Combining bioclinical parameters with liver stiffness measurement (LSM) has improved the diagnostic performance of vibration‐controlled transient elastography (VCTE) for detection of advanced fibrosis in patients with chronic liver disease. However, this approach has not yet been tested in liver transplantation (LT) recipients.
Tamoore Arshad   +11 more
wiley   +1 more source

Protective Properties of FOXO1 Inhibition in a Murine Model of Non-alcoholic Fatty Liver Disease Are Associated With Attenuation of ER Stress and Necroptosis

open access: yesFrontiers in Physiology, 2020
AimThe pathogenesis of non-alcoholic fatty liver disease is currently unclear, however, lipid accumulation leading to endoplasmic reticulum stress appears to be pivotal in the process. At present, FOXO1 is known to be involved in NAFLD progression.
Hao-ran Ding   +19 more
doaj   +1 more source

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