Comparative characterisation of human and ovine non-aureus staphylococci isolated in Sardinia (Italy) for antimicrobial susceptibility profiles and resistance genes. [PDF]
Epidemiol Infect, 2021 Longheu CM +6 more
europepmc +1 more source
Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
British Journal of Clinical Pharmacology, EarlyView.Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
Beyond the Wild MRSA: Genetic Features and Phylogenomic Review of mecC-Mediated Methicillin Resistance in Non-aureus Staphylococci and Mammaliicocci [PDF]
Methicillin resistance, mediated by the mecA gene in staphylococci and mammaliicocci, has caused tremendous setbacks in the use of antibiotics in human and veterinary medicine due to its high potential of presenting the multidrug resistance (MDR ...
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British Journal of Clinical Pharmacology, EarlyView.Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari +6 more
wiley +1 more source
Exploring the phylogenetic diversity and antimicrobial activity of non-<i>aureus staphylococci</i> and <i>mammaliicocci</i> isolated from teat apices of organic dairy cows. [PDF]
Front MicrobiolPeña-Mosca F +7 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott +16 more
wiley +1 more source
In vitro regulation of Staphylococcus aureus growth and virulence by bovine non-aureus staphylococci : potential implications for udder health [PDF]
Staphylococcus aureus remains one of the most common causative agents of bovine mastitis because of its pathogenicity, contagiousness, capability to persist in the mammary gland, colonization of skin, and poor cure rates when causing intramammary ...
Toledo-Silva, Bruno
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Detection of icaA, icaD, and bap genes and biofilm production in Staphylococcus aureus and non-aureus staphylococci isolated from subclinical and clinical bovine mastitis [PDF]
Arquivo Brasileiro de Medicina Veterinária e ZootecniaA. Salina +5 more
doaj +2 more sources
One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification
Biotechnology and Bioengineering, EarlyView.One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal +8 more
wiley +1 more source
Non-aureus Staphylococci Cause the Spontaneous Cure or Persistent Infection of Major Bovine Mastitis Pathogens in the Murine Mammary Glands. [PDF]
Animals (Basel)Suriyasathaporn W +8 more
europepmc +1 more source