Results 41 to 50 of about 20,435,494 (220)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Higher-Order First Integrals of Autonomous Non-Riemannian Dynamical Systems
, 2023 We consider autonomous holonomic dynamical systems defined by equations of the form q¨a=−Γbca(q)q˙bq˙c−Qa(q), where Γbca(q) are the coefficients of a symmetric (possibly non-metrical) connection and −Qa(q) are ...
Antonios Mitsopoulos +2 more
core +2 more sources
Uniform exponential stability of linear periodic systems in a Banach space
Electronic Journal of Differential Equations, 2001 This article is devoted to the study of linear periodic dynamical systems, possessing the property of uniform exponential stability. It is proved that if the Cauchy operator of these systems possesses a certain compactness property, then the asymptotic ...
David N. Cheban
doaj
Dynamical systems of modified Gauss–Bonnet gravity: cosmological implications
European Physical Journal C: Particles and FieldsIn this paper, we derive the field equations of modified Gauss–Bonnet gravity termed as f(R, G) gravity for the non-flat Friedmann–Robertson–Walker (FRW) spacetime.
Ashutosh Singh
doaj +1 more source
The numerical computation of connecting orbits in dynamical systems [PDF]
, 1990 Beyn W-J. The numerical computation of connecting orbits in dynamical systems. IMA Journal of Numerical Analysis. 1990;10(3):379-405.Structural changes in dynamical systems are often related to the appearance or disappearance of orbits connecting two ...
Beyn, Wolf-Jürgen
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dynamics for a non-linear and non-autonomous compartmental system
, 2016 We study the long-time behavior of the amount of material within the compartments of a compartmental system for which the flow of material does not have to be instantaneous and may even take an infinite time to occur. Results on the estructure of minimal sets for monotone skew-product semiflows, previously obtained by the authors, are applied to this ...
Muñoz Villarragut, Víctor +2 more
openaire +2 more sources
Well-posedness results for non-autonomous dissipative complementarity systems [PDF]
, 2006 This paper deals with the well-posedness of a class of nonsmooth dynamical systems: dissipative complementarity systems. Both the linear and the nonlinear cases are treated, and the systems are non-autonomous.
Thibault, Lionel, Brogliato, Bernard
core +4 more sources