Results 81 to 90 of about 210,904 (138)

Ab initio RNA folding

, 2014
RNA molecules are essential cellular machines performing a wide variety of functions for which a specific three-dimensional structure is required. Over the last several years, experimental determination of RNA structures through X-ray crystallography and
Cragnolini, Tristan, Derreumaux, Philippe, Pasquali, Samuela   +2 more
core   +1 more source

Genetic Code: A New Understanding of Codon - Amino Acid Assignment

, 2006
In this work it is shown that 20 canonical amino acids (AAs) within genetic code appear to be a whole system with strict AAs positions; more exactly, with AAs ordinal number in three variants; first variant 00-19, second 00-21 and third 00-20.
Black, Damjanović, Duve, Kyte, MILOJE M. RAKOČEVIĆ, Rakočević, Rakočević, ZVONIMIR M. DAMJANOVIĆ   +7 more
core   +1 more source

Evidence from Meteorites for Multiple Possible Amino Acid Alphabets for the Origins of Life [PDF]

A key question for the origins of life is understanding which amino acids made up the first proteins synthesized during the origins of life. The canonical set of 20 - 22 amino acids used in proteins are all alpha-amino, alpha-hydrogen isomers that ...
Burton, A. S., Callahan, M. P., Dworkin, J. P., Elsila, J. E., Glavin, D. P.   +4 more
core   +1 more source

Non-Canonical Amino Acids in Analyses of Protease Structure and Function. [PDF]

Int J Mol Sci, 2023
Goettig P, Koch NG, Budisa N.
europepmc   +1 more source

Permanent draft genome sequence of Frankia sp. NRRL B-16219 reveals the presence of canonical nod genes, which are highly homologous to those detected in Candidatus Frankia Dg1 genome [PDF]

, 2017
Frankia sp. NRRL B-16219 was directly isolated from a soil sample obtained from the rhizosphere of Ceanothus jepsonii growing in the USA. Its host plant range includes members of Elaeagnaceae species.
Furnholm, Teal, Ghodhbane-Gtari, Faten, Gtari, Maher, Ktari, Amir, Nouioui, Imen, Swanson, Erik, Tisa, Louis S.   +6 more
core   +1 more source

Comparative genomic analysis of trypanosomatid protists illuminates an extensive change in the nuclear genetic code

mBio
Trypanosomatids are among the most extensively studied protists due to their parasitic interactions with insects, vertebrates, and plants. Recently, Blastocrithidia nonstop was found to depart from the canonical genetic code, with all three stop codons ...
Kristína Záhonová, Zoltán Füssy, Amanda T. S. Albanaz, Anzhelika Butenko, Ambar Kachale, Natalya Kraeva, Arnau Galan, Alexandra Zakharova, Bojana Stojanova, Jan Votýpka, Alexei Y. Kostygov, Viktoria V. Spodareva, Marina N. Malysheva, Alexander O. Frolov, Igor B. Rogozin, Zdeněk Paris, Leoš Shivaya Valášek, Vyacheslav Yurchenko, Julius Lukeš   +18 more
doaj   +1 more source

Recent advances in biosynthesis of non-canonical amino acids and their potentials in strain engineering

Results in Engineering
Non-canonical amino acids (ncAAs), as derivatives of canonical amino acids (cAAs), when specifically incorporated into proteins, could enrich protein functions.
Zhen Hou, Junkai Tuo, Xiaoyan Ma, Yi-Xin Huo   +3 more
doaj   +1 more source

Practical Approaches to Genetic Code Expansion with Aminoacyl-tRNA Synthetase/tRNA Pairs

CHIMIA
Genetic code expansion (GCE) can enable the site-selective incorporation of non-canonical amino acids (ncAAs) into proteins. GCE has advanced tremendously in the last decade and can be used to create biorthogonal handles, monitor and control proteins ...
Anton Natter Perdiguero, Alexandria Deliz Liang   +1 more
doaj   +1 more source

Site-specific incorporation of biophysical probes into NF-ĸB with non-canonical amino acids. [PDF]

Methods, 2023
Chen W, Gunther TR, Baughman HER, Komives EA.   +3 more
europepmc   +1 more source

Non-canonical amino acids as a tool for the thermal stabilization of enzymes. [PDF]

Protein Eng Des Sel, 2023
Lugtenburg T, Gran-Scheuch A, Drienovská I.   +2 more
europepmc   +1 more source