Results 101 to 110 of about 444,424 (262)
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Design of a Non-Circular Gear-Crank Slider Baler Mechanism Considering Slider Acceleration
Engineering TransactionsA design method considering slider acceleration is proposed to reduce vibration and improve the working efficiency of a non-circular gear-crank slider baler mechanism.
Jian WANG, Chenjie WANG, Long MIAO
doaj +1 more source
Fiber-Reinforced Polymer-Confined Non-Circular Columns with Shape Modification: A Comprehensive Review. [PDF]
Polymers (Basel), 2022 He C, Zeng JJ.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Non-circular CBCT orbit design and realization on a clinical robotic C-arm for metal artifact reduction. [PDF]
Proc SPIE Int Soc Opt Eng, 2022 Ma Y +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Dynamic Characteristic Testing Device and Experiment Analysis of Non-circular Gear
Jixie chuandong, 2015 For the study of the dynamic characteristics of non- circular gear,a transmission box of non-circular gear is designed. According to its dynamic characteristics,a measurement scheme is put forward and the electric parts of its relevant power system ...
Liu Yongping, Xian Xilon, Wang Peng
doaj
SensorsA circular capacitive rainfall sensor can operate from non-touch mode to touch mode; that is, under the action of enough rainwater, its movable electrode plate can form a circular contact area with its fixed electrode plate.
Xiao-Ting He +4 more
doaj +1 more source
Geometric Specification of Non-Circular Pulleys Made with Various Additive Manufacturing Techniques. [PDF]
Materials (Basel), 2021 Krawiec P +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source