Results 81 to 90 of about 444,424 (262)

Mechanism Analysis and Optimization Design of Exoskeleton Robot with Non-Circular Gear–Pentabar Mechanism

Machines
To address the complex structure of existing rod mechanism exoskeleton robots and the difficulty in solving the motion trajectory of multi−rod mechanisms, an exoskeleton knee robot with a differential non−circular gear–pentarod mechanism is designed ...
Guibin Wang, Maile Zhou, Hao Sun, Zhaoxiang Wei, Herui Dong, Tingbo Xu, Daqing Yin   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Discovery of natural non-circular permutations in non-coding RNAs. [PDF]

Nucleic Acids Res, 2023
Eckert I, Friedrich R, Weinberg CE, Weinberg Z.   +3 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

基于折算齿形法的非封闭型非圆齿轮齿廓绘制

Jixie chuandong, 2014
The enclosed pitch curve of logarithmic spiral of non-circular gear tooth profile is generated in CAXA via the gear meshing theory and the conversion method of tooth profile for the enclosed pitch curve of non-circular gear tooth profile generation ...
王鹏, 刘永平, 何贵平
doaj  

Non-Circular Signal DOA Estimation with Nested Array via Off-Grid Sparse Bayesian Learning. [PDF]

Sensors (Basel), 2023
Dong X, Zhao J, Sun M, Zhang X.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

非圆齿轮传动弯曲强度计算方法研究

Jixie chuandong, 2011
According to the machining principle,the tooth profile mathematical model of non-circular gear is established,and differences of the tooth profile are compared between the non-circular gear and its equivalent cylindrical gear.On this basis,the ...
李纪强, 刘忠明
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Revealing pelvic structures in the presence of metal hip prothesis via non-circular CBCT orbits. [PDF]

Proc SPIE Int Soc Opt Eng, 2023
Reynolds T, Ma Y, Wang T, Mei K, Noël PB, Gang GJ, Stayman JW.   +6 more
europepmc   +1 more source