Results 61 to 70 of about 444,424 (262)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Error Detection and Classification of Tangential Radial Single Machining of Non-Circular Gear
MATEC Web of Conferences, 2016 The studies on non-circular gear cutting and using errors were generally based on theory of cylindrical gear errors, and the similarities and differences between cylindrical gear and non-circular gear were combined to study the change rule of non ...
Dai Jianqing, Wang Shengze
doaj +1 more source
Non-Asymptotic Confidence Sets for Circular Means
Entropy, 2016 The mean of data on the unit circle is defined as the minimizer of the average squared Euclidean distance to the data. Based on Hoeffding’s mass concentration inequalities, non-asymptotic confidence sets for circular means are constructed which are ...
Thomas Hotz +2 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Design and Kinematics Analysis of Non-circular Belt Transmission
Jixie chuandong, 2015 To the problems of difficult to meet the complex parts structure manufacturing of a circular belt drive mechanical transmission on the time-varying transmission ratio and specific output requirements,a non-circular belt drive mechanism of variable speed ...
Ju Hongxiang
doaj
Key Technologies and Applications of the Design and Manufacturing of Non-Circular TBMs
Engineering, 2017 With the rapid development of the exploitation of underground space, more and more large- or super-large-diameter tunnel-boring machines (TBMs) are being employed to construct underground space projects.
Jianbin Li
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Jixie chuandong, 2011 Based on the non-circular gear tooth profile forming principle,the motion model of tool rack is established.Using the secondary development tool VBA of AutoCAD,the non-circular gear solid model is gotten by simulating the process of non-circular gear ...
黄忠超, 蓝兆辉
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source