Results 91 to 100 of about 512,574 (282)

C.I. Lewis, E.J. Nelson, and the Modern Origins of Connexive Logic

open access: yesOrganon F, 2019
Modern logic owes an important debt to C.I. Lewis and his students. In addition to Lewis’s five modal logics, they are responsible for the creation (or discovery) of the logic of analytic implication and connexive logic.
Edwin Mares, Francesco Paoli
doaj   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Conditions of applicability of classical logic to philosophical reasoning

open access: yesRUDN Journal of Philosophy, 2018
. The conditions for the applicability of the classical logic of statements to philosophical reasonings are investigated. This research is carried out within the framework of various semantics for many-valued logics.
S A Pavlov
doaj   +1 more source

Focusing and Polarization in Intuitionistic Logic [PDF]

open access: yes, 2007
A focused proof system provides a normal form to cut-free proofs that structures the application of invertible and non-invertible inference rules. The focused proof system of Andreoli for linear logic has been applied to both the proof search and the ...
Liang, Chuck, Miller, Dale
core   +7 more sources

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

open access: yesAdvanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang   +3 more
wiley   +1 more source

Teoria kategorii i niektóre jej logiczne aspekty

open access: yesZagadnienia Filozoficzne w Nauce, 2018
This article is intended for philosophers and logicians as a short partial introduction to category theory (CT) and its peculiar connection with logic. First, we consider CT itself.
Mariusz Stopa
doaj  

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

open access: yesAdvanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka   +3 more
wiley   +1 more source

Problem Libraries for Non-Classical Logics

open access: yesEPiC Series in Computing, 2018
Problem libraries for automated theorem proving (ATP) systems play a crucial role when developing, testing, benchmarking and evaluating ATP systems for classical and non-classical logics. We provide an overview of existing problem libraries for some important non-classical logics, namely first-order intuitionistic and first-order modal logics.
Jens Otten, Thomas Raths
openaire   +2 more sources

Climate Action Impacts on Steelmaking Emissions of Persistent Organic Pollutants Highlight a Gap Between the Paris Agreement and the Stockholm Convention

open access: yesAdvanced Science, EarlyView.
Emissions of unintentionally produced persistent organic pollutants (UPOPs) and global warming are two major environmental challenges. But their governance has largely evolved in parallel, leaving the toxicity implications of climate‐driven industrial transitions poorly understood.
Yuxiang Sun   +7 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

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