Results 101 to 110 of about 963,524 (371)
Molecular Cancer, 2017 To overcome the hostile hypoxic microenvironment of solid tumors, tumor cells secrete a large number of non-coding RNA-containing exosomes that facilitate tumor development and metastasis.
Mei Xue +10 more
semanticscholar +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
Frontiers in Microbiology, 2015 Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and infection control challenge. In this study, we investigated the epidemiological and molecular differences of CRAB, and the threatening factors for contributing to ...
Yaowen eChang +10 more
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
The Epigenetics of Non-coding RNA [PDF]
, 2011 Summary Non-coding RNAs (ncRNAs) have been implicated in the epigenetic marking of many genes. Short regulatory ncRNAs, including miRNAs, siRNAs, piRNAs and snoRNAs as well as long ncRNAs such as Xist and Air are discussed in light of recent research of mechanisms regulating chromatin marking and RNA editing.
Collins, L., Schönfeld, B., Chen, X.
openaire +2 more sources
Exercise Controls Non-Coding RNAs [PDF]
Cell Metabolism, 2015 The mechanisms by which exercise regulates physiological cardiac growth and protects against maladaptive remodeling of the heart have been long sought after. In this issue, Liu et al. (2015) report that microRNAs are important regulators of exercise responses in the heart.
Stefanie Dimmeler, Shizuka Uchida
openaire +3 more sources
Shapes of interacting RNA complexes [PDF]
arXiv, 2014 Shapes of interacting RNA complexes are studied using a filtration via their topological genus. A shape of an RNA complex is obtained by (iteratively) collapsing stacks and eliminating hairpin loops. This shape-projection preserves the topological core of the RNA complex and for fixed topological genus there are only finitely many such shapes.Our main ...
arxiv
Quality Assessment of Domesticated Animal Genome Assemblies
Bioinformatics and Biology Insights, 2015 The era of high-throughput sequencing has made it relatively simple to sequence genomes and transcriptomes of individuals from many species. In order to analyze the resulting sequencing data, high-quality reference genome assemblies are required. However,
Stefan E. Seemann +3 more
doaj +1 more source
Molecular Cancer, 2015 The imprinted oncofetal long non-coding RNA (lncRNA) H19 is expressed in the embryo, down-regulated at birth and then reappears in tumors. Its role in tumor initiation and progression has long been a subject of controversy, although accumulating data ...
E. Raveh +3 more
semanticscholar +1 more source