Results 221 to 230 of about 970,725 (346)
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
The Role of Long Non-Coding RNA in Anxiety Disorders: A Literature Review. [PDF]
Int J Mol SciLópez-Rocha LD +7 more
europepmc +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Advanced Biology, EarlyView.Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang +8 more
wiley +1 more source
Long non-coding RNA in IgA nephropathy: a comprehensive review. [PDF]
Ren FailHuang X, Chen L, He J, Tang J, Mou Z.
europepmc +1 more source
Cascade transcription of mRNA-type long non-coding RNAs (mlonRNAs) and local chromatin remodeling [PDF]
, 2009 Kouji Hirota, Kunihiro Ohta
openalex +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Urinary long non-coding RNA GAS5 as a noninvasive diagnostic biomarker for renal fibrosis. [PDF]
Ren FailYu Y, Niu YY, Zhang YY, Yu C.
europepmc +1 more source
Advanced Functional Materials, EarlyView.In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García +23 more
wiley +1 more source
Role of Non-Coding RNAs in Stroke [PDF]
Stroke, 2018 Tiedt, Steffen, Dichgans, Martin
openaire +4 more sources