Results 231 to 240 of about 970,725 (346)

Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim, Hwi Won Seo, Kyuri Lee, Dongeun Yong, Yoon Kyung Park, Yujin Lee, Solip Lee, Do‐Wan Kim, Dajeong Kim, Choong‐Min Ryu   +9 more
wiley   +1 more source

Functions and mechanisms of long non-coding RNA in esophageal squamous cell carcinoma (Review). [PDF]

Oncol Lett
Lin Y, Lv Z, Xie H, Zhao W, Pu R, Zhang Z, Jin H.   +6 more
europepmc   +1 more source

Non-Protein Coding RNAs

, 2008
Nils G. Walter, Sarah A. Woodson, Robert Batey   +2 more
openalex   +1 more source

Deletion of Gtl2 , imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice [PDF]

, 2009
Nozomi Takahashi, Akira Okamoto, Ryota Kobayashi, Motomu Shirai, Yayoi Obata, Hidehiko Ogawa, Yusuke Sotomaru, Tomohiro Kono   +7 more
openalex   +1 more source

膵癌とlong non-coding RNA

, 2016
賢至 高橋, 陽平 北野, 雄一 牧野, 勝計 羽田   +3 more
semanticscholar   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

RNA Sequencing Reveals the Long Non-Coding RNA Signature in Psoriasis Keratinocytes and Identifies CYDAER as a Long Non-Coding RNA Regulating Epidermal Differentiation. [PDF]

Exp Dermatol
Freisenhausen JC, Luo L, Kelemen E, Elton J, Skoog V, Pivarcsi A, Sonkoly E.   +6 more
europepmc   +1 more source

Short non-coding RNA biology and neurodegenerative disorders: novel disease targets and therapeutics [PDF]

, 2009
Marc S. Weinberg, Matthew J. A. Wood
openalex   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

PANDORA-Seq Unveils the Hidden Small Non-Coding RNA Landscape in Hypopharyngeal Carcinoma. [PDF]

Int J Mol Sci
Pu M, Shi L, Ma H, Tao C, Zhang Y, Bu Y, Ye J.   +6 more
europepmc   +1 more source