Results 261 to 270 of about 894,957 (355)
The epitranscriptome meets non-coding RNA: m6A-mediated regulation in oncogenesis and therapy. [PDF]
Ramalingam PS +7 more
europepmc +1 more source
IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang +18 more
wiley +1 more source
Long non‑coding RNA NKILA regulates the JAK2/STAT3 pathway to exacerbate TGF‑β1‑mediated renal fibrosis. [PDF]
Han Y +5 more
europepmc +1 more source
ELABELA Targets Mitochondria to Modulate Heart Development
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang +22 more
wiley +1 more source
Polymorphisms of long non-coding RNA HOTAIR and susceptibility to gastrointestinal cancers: A meta-analysis. [PDF]
Xie H, Li Y, Zhao W, Lin Y.
europepmc +1 more source
Non-coding RNAs as modulators of the cardiac fibroblast phenotype
Maria-Teresa Piccoli +2 more
openalex +2 more sources
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
The Stiff Side of Cancer: How Matrix Mechanics Rewrites Non-Coding RNA Expression Programs. [PDF]
Campos-Parra AD +6 more
europepmc +1 more source

