Results 271 to 280 of about 894,957 (355)

Center Molecular Mechanisms of Non-coding RNAs and RNA Modifications in Colorectal Cancer [PDF]

T.Q. Yu
openalex   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Conserved non-coding RNA motifs influence the neuropathogenicity of Simbuviruses: Molecular dissection in the Schmallenberg virus model. [PDF]

PLoS Pathog
Bonil L, Wiggers L, Dumont H, Caporale M, Nollevaux MC, Nicaise C, Muylkens B, Coupeau D.   +7 more
europepmc   +1 more source

Long non-coding RNA MALAT1 in hematological malignancies and its clinical applications

Chunlan Zhang, Yun Qin, Yu Wu, Heng Xu, Yang Shu   +4 more
openalex   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Gut Microbiota-Non-Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation. [PDF]

Adv Sci (Weinh)
Chen B, Chen G, Leng X, Li Q, Wu W, Wu W, Liu Z, Zhong Z, Zheng X, Kang W, Ren F, Zhang Y, Chen J.   +12 more
europepmc   +1 more source

Up‐regulation of HOXA‐AS2 and MEG3 long non‐coding RNAs acts as a potential peripheral biomarker for bipolar disorder [PDF]

Maryamsadat Hosseini, Mohammad Javad Mokhtari   +1 more
openalex   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Seeing and sensing the heart: integrating non-coding RNA biomarkers with imaging in cardiovascular medicine. [PDF]

Eur Heart J Imaging Methods Pract
Kleeberger JA, Di Venanzio L, Atzemian N, Ruschitzka F, Paneni F.   +4 more
europepmc   +1 more source