Results 271 to 280 of about 895,028 (332)

Role of non-coding RNA through nanomedicine: the novel therapeutic and diagnostic approaches. [PDF]

Bioimpacts
Khoshnevisan K, Eslamizade MJ, Shams F.
europepmc   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source

DNA/RNA hybrid profiling in autistic patients: A focus on mRNA and non-coding RNA variations. [PDF]

PLoS One
Kianmehr L, MokhtarZadeh K, Yilmaz Z, Darzi Ramandi H, Mehmetbeyoglu Duman E, Funda Sener E, Taheri S, Rassoulzadegan M.   +7 more
europepmc   +1 more source

Long Non-Coding RNA Nuclear-Enriched Abundant Transcript 1 (<i>NEAT1</i>) Facilitates Foam Cell Formation and Atherosclerosis Progression Through the miR-17-5p/Itchy E3 Ubiquitin Protein Ligase (ITCH)/Liver Kinase B1 (LKB1) Axis

Haifen Huang, Bin Peng, Qingyong Chen, Yi Wang, Li Ren   +4 more
openalex   +2 more sources

<p>Long non-coding RNA TUG1-mediated down-regulation of KLF4 contributes to metastasis and the epithelial-to-mesenchymal transition of colorectal cancer by miR-153-1</p>

, 2019
Hongjin Shao, Dian-Bo Dong, Feng Shao
openalex   +2 more sources

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

A long non-coding RNA Leat1 mediates the hormone responsiveness of EfnB2 during male urogenital development. [PDF]

Commun Biol
Mattiske D, Bernard P, Gradie PE, Behringer RR, Overbeek PA, J O'Neill R, Phillips T, Stewart M, Youngson N, Tarulli G, Pask AJ.   +10 more
europepmc   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Immune-Related Protein and Non-Coding RNA Cargo of Extracellular Vesicles Participate in the Chronic Inflammation Induced by HIV Infection. [PDF]

J Extracell Biol
Doriguêtto Gravina H, Castro RC, Gonçalves AM, Lima JO, Sugiyama FHC, Moreira BC, Antunes MDSM, Fontanari C, Bollela VR, Lamarre YY, Almeida F, Kashima S, Saraiva M, Osório N, Frantz FG.   +14 more
europepmc   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source