Results 271 to 280 of about 963,524 (371)

Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction

open access: yesAdvanced Materials, EarlyView.
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin   +17 more
wiley   +1 more source

The Role of Long Non-Coding RNA in the Pathogenesis of Psoriasis. [PDF]

open access: yesNoncoding RNA
Kiełbowski K   +3 more
europepmc   +1 more source

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis [PDF]

open access: green, 2010
Rajnish A. Gupta   +17 more
openalex   +1 more source

Hydrogel‐Mediated Preservation of Live Tumor Explants for Drug Development in Peritoneal Metastases

open access: yesAdvanced Materials, EarlyView.
This study presents a hyaluronan‐based hydrogel platform preserving the native tumor microenvironment (morphology, tissue composition, histology) of patient‐derived explants from peritoneal metastases, enabling clinically relevant drug screening. Hydrogel properties such as stiffness and degradation are crucial for longer‐term histoculture.
Kenny Zhuoran Wu   +16 more
wiley   +1 more source

Non-coding RNA in cartilage regeneration: regulatory mechanism and therapeutic strategies. [PDF]

open access: yesFront Bioeng Biotechnol
Wen M   +6 more
europepmc   +1 more source

CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer [PDF]

open access: hybrid, 2010
Amaia Lujambio   +8 more
openalex   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

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