Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Associations between executive functions, coaches' evaluation, and performance development in youth soccer. [PDF]
Knöbel S +5 more
europepmc +1 more source
Recent Progress on Flexible Multimodal Sensors: Decoupling Strategies, Fabrication and Applications
In this review, we establish a tripartite decoupling framework for flexible multimodal sensors, which elucidates the underlying principles of signal crosstalk and their solutions through material design, structural engineering, and AI algorithms. We also demonstrate its potential applications across environmental monitoring, health monitoring, human ...
Tao Wu +10 more
wiley +1 more source
Understanding of ironic and literal utterances in 4-9-year-old typically developing children: role of age, narrative skills, emotion comprehension and executive functions. [PDF]
Oshchepkova E +2 more
europepmc +1 more source
Respiratory Signal Processing and Analysis Using Flexible Capacitive Sensor Data
Capacitive pressure sensors based on poly(glycerol sebacate) (PGS) substrates are developed for continuous, non‐invasive respiratory monitoring. Integrated with a signal processing algorithm, they enable accurate tracking of thoracic expansion and retraction.
Bernardo A. Vicente +3 more
wiley +1 more source
Integrative social cognition remediation with social skills training for adults: PICSIS - pilot study in autism and schizophrenia. [PDF]
Visser M +9 more
europepmc +1 more source
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
The Impact of Executive Functions on Metaphonological Skills: Correlation and Treatment Implication for ADHD Children. [PDF]
Piccolo A +11 more
europepmc +1 more source
A graphene‐based bowtie plasmonic nanotweezer is designed and optimized using particle swarm optimization and transfer matrix analysis. The structure achieves strong field confinement, delivering trapping forces up to 6 nN W−1 for 10 nm bioparticles with sixfold lower power requirements than conventional designs.
Saba Ebrahimpanah +2 more
wiley +1 more source
Gaze-Speech Coordination During Narration in Autism Spectrum Disorder and First-Degree Relatives. [PDF]
Xing J +6 more
europepmc +1 more source

