Results 31 to 40 of about 74,857 (265)

Improved Detection Schemes for Non-coherent Pulse-Position Modulation

open access: yesWireless Personal Communications, 2023
Energy-detection (ED) pulse-position modulation (PPM) receivers exhibit poor performance and low rates. Coherent receivers do not have such problems but their complexity is unacceptable. We propose two detection schemes to increase the performance of non-coherent PPM receivers.
openaire   +2 more sources

Towards Implementation of Neural Networks for Non-Coherent Detection MIMO systems

open access: yes2022 IEEE 96th Vehicular Technology Conference (VTC2022-Fall), 2022
In this paper, we propose the use of quantized neural networks to perform non coherent MIMO detector in sub-TeraHertz (THz) communications. Implementing neural networks is challenging because operations are performed using a high number of bits. This results in slow and energy consuming computations.
Falempin, Alexis   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

PEP analysis of SDP-based non-coherent signal detection [PDF]

open access: yes2007 IEEE International Symposium on Information Theory, 2007
In multi-antenna communication systems, channel information is often not known at the receiver. To fully exploit the bandwidth resources of the system and ensure the practical feasibility of the receiver, the channel parameters are often estimated and then employed in the design of signal detection algorithms. However, sometimes communication can occur
Mihailo Stojnic   +2 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

An Enhanced Non-Coherent Pre-Filter Design for Tracking Error Estimation in GNSS Receivers

open access: yesSensors, 2017
Tracking error estimation is of great importance in global navigation satellite system (GNSS) receivers. Any inaccurate estimation for tracking error will decrease the signal tracking ability of signal tracking loops and the accuracies of position fixing,
Zhibin Luo   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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