Results 21 to 30 of about 422,178 (239)

Leveraging the South African Diabetes Prevention Programme to screen for chronic kidney disease: an observational study

BMJ Open, 2023
Objective To evaluate the viability of leveraging an existing screening programme (the South African Diabetes Prevention Programme (SA-DPP)) to screen for chronic kidney disease (CKD), by assessing the yield of CKD cases among those participating in the ...
Cindy George, Andre P Kengne, Nasheeta Peer, Jillian Hill, Unati Nqebelele   +4 more
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

The association of self-rated health with physical activity and demographic factors: a study in primary care from Northwest of Iran

BMC Primary Care
Background Self-rated health (SRH) is an international measure and indicator of mortality and morbidity that can be used as a mortality predictor in adulthood.
Hanieh Moradi, Abouzar Raeisvandi, Mahdie Bahrami, Mohammad Amerzadeh, Mozhgan Abbasi, Zahra Hosseinkhani, Mehdi Osooli   +6 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Temporal patterns in pre-hospital emergency medical services responses in Qazvin, Iran

Discover Social Science and Health
Background Pre-hospital care plays a crucial role in the management and control of emergency patients and medical emergencies. The faster and more accurate the performance of medical emergency bases in terms of time and response, the lower the mortality ...
Fariba Naseri, Omid Khosravizadeh, Yousof Akbari Shahrestanaki, Bahman Ahadinezhad, Mohammad Amerzadeh   +4 more
doaj   +1 more source

Adult food choices in association with the local retail food environment and food access in resource-poor communities: a scoping review

BMC Public Health, 2023
Background There is a growing body of research on local retail food environments globally in both urban and rural settings. Despite this, little research has been conducted on adult food choices, local retail environments, and healthy food access in ...
Samukelisiwe S. Madlala, Jillian Hill, Ernesta Kunneke, Tatum Lopes, Mieke Faber   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The effects of Pranayama breathing exercise on symptom burden among women with breast cancer undergoing chemotherapy: a randomized controlled trial

BMC Complementary Medicine and Therapies
Background Pranayama breathing exercises may help reduce the burden of chemotherapy-induced symptoms in women with breast cancer. The aim of this study was to determine the effect of pranayama breathing exercise on symptom burden in women with breast ...
Maryam Momeni, Marzieh Khatooni, Ahad Alizadeh, Sima Mohebbi   +3 more
doaj   +1 more source

Use of medical administrative data for the surveillance of psychotic disorders in France

BMC Psychiatry, 2017
Background Psychotic disorders are among the most severe psychiatric disorders that have great effects on the individuals and the society. For surveillance of chronic low prevalence conditions such as psychotic disorders, medical administrative databases
Christine Chan Chee, Francis Chin, Catherine Ha, Nathalie Beltzer, Christophe Bonaldi   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source