Results 41 to 50 of about 435,138 (258)

Environmental risks and non-communicable diseases [PDF]

BMJ, 2019
Annette Prüss-Ustün and colleagues consider the role of air pollution and other environmental risks in non-communicable diseases and actions to reduce ...
Prüss-Ustün, Annette, van Deventer, Emilie, Mudu, Pierpaolo, Campbell-Lendrum, Diarmid, Vickers, Carolyn, Ivanov, Ivan, Forastiere, Francesco, Gumy, Sophie, Dora, Carlos, Adair-Rohani, Heather, Neira, Maria   +10 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Prevalence of plasma lipid abnormalities and associated risk factors among Iranian adults based on the findings from STEPs survey 2021

Scientific Reports, 2023
The study aimed to estimate the prevalence of lipid abnormalities in Iranian adults by demographic characterization, geographical distribution, and associated risk factors using national and sub-national representative samples of the STEPs 2021 survey in
Javad Khanali, Erfan Ghasemi, Mohammad-Mahdi Rashidi, Naser Ahmadi, Seyyed-Hadi Ghamari, Mohammadreza Azangou-Khyavy, Mohammad-Reza Malekpour, Mohsen Abbasi-Kangevari, Seyedeh Melika Hashemi, Mohammadreza Naderian, Negar Rezaei, Arezou Dilmaghani-Marand, Yosef Farzi, Ameneh Kazemi, Moein Yoosefi, Amirali Hajebi, Shahabeddin Rezaei, Sina Azadnajafabad, Nima Fattahi, Maryam Nasserinejad, Elham Abdolhamidi, Rosa Haghshenas, Nazila Rezaei, Shirin Djalalinia, Bagher Larijani, Farshad Farzadfar   +25 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Predictors of sleep quality subscales among medical university employees in Iran: a Bayesian analysis of cross-sectional data

BMC Public Health
Background Poor sleep quality is prevalent among medical employees and adversely affects their performance and well-being. Limited evidence exists regarding behavioral, psychological, and health-related risk factors for poor sleep quality in medical ...
Zahra Hosseinkhani, Edris Kakemam, Maryam Hadji, Neda Mohammadi   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The impact of good governance on organizational health with the mediating role of organizational accountability: considering the influence of demographic and organizational variables

BMC Health Services Research
Background Human resources are the critical element of organizations and serve as the economic engine of countries. Human resources play a crucial role in gaining competitive advantage.
Taiebeh Taheri, Mohammad Amerzadeh, Ahad Alizadeh, Rohollah Kalhor   +3 more
doaj   +1 more source

Burden of stroke in North Africa and Middle East, 1990 to 2019: a systematic analysis for the global burden of disease study 2019

BMC Neurology, 2022
Background While several studies investigated the epidemiology and burden of stroke in the North Africa and Middle East region, no study has comprehensively evaluated the age-standardized attributable burden to all stroke subtypes and their risk factors ...
Ataollah Shahbandi, Parnian Shobeiri, Sina Azadnajafabad, Sahar Saeedi Moghaddam, Yeganeh Sharifnejad Tehrani, Narges Ebrahimi, Nazila Rezaei, Mohammad-Mahdi Rashidi, Seyyed-Hadi Ghamari, Mohsen Abbasi-Kangevari, Sogol Koolaji, Rosa Haghshenas, Negar Rezaei, Bagher Larijani, Farshad Farzadfar   +14 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source