Results 131 to 140 of about 30,785,842 (283)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Revista Chilena de Radiología60 pacientes, derivados para angiografía tomográfica, 58% de ellos del sexo masculino, con edades en el rango de 16 a 81 años y pesos de 43 a 100 kg fueron estudiados con un protocolo que incluyó inyección de un bolo piloto de 16 ml de medio de contraste,
Mauricio Vergara E +2 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Variation in the perception of an L2 contrast : a combined phonetic and phonological account [PDF]
, 2009 The present study argues that variation across listeners in the perception of a non-native contrast is due to two factors: the listener-specic weighting of auditory dimensions and the listener-specic construction of new segmental representations.
Hamann, Silke
core
, 2013 Languages in Contrast aims to publish contrastive studies of two or more languages. Any aspect of language may be covered, including vocabulary, phonology, morphology, syntax, semantics, pragmatics, text and discourse, stylistics, sociolinguistics and ...
BERNARDINI, SILVIA
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Advanced design and experimental validation of MRI contrast agents for fluid pressure mapping using microbubbles [PDF]
, 2009 This work is related to monitoring fluid pressure using Magnetic Resonance Imaging or MRI and includes numerical simulations and experimental MRI. The nature of this study is such that techniques other than MRI have been extensively used to assess the ...
Morris, RH, Morris, Robert H
core
EFFECT OF N-ACETYLCYSTEINE ON DERANGED RENAL FUNCTIONS IN PATIENT RECEIVING NON IONIC RADIO CONTRAST
Pakistan Armed Forces Medical Journal, 2013 Objective: To determine the effect of N-Acetylcysteine (NAC) on deranged renal functions in patients receiving non-ionic contrast. Study Design: Quasi- experimental study.
Dr Mahjabeen Mehmood Kamal +1 more
doaj +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source