Results 71 to 80 of about 13,883,468 (305)

Mechanisms of Starch-Polyphenol Interactions, Structural Characterization, and Their Impact on Functional Properties: A review

Shipin gongye ke-ji
Starch, the primary source of carbohydrates in food, plays a crucial role in nutrition and health owing to its digestive properties and functional regulation and has been a subject of extensive research. Recently, researchers have non-covalently combined
Yanchi WANG, Weiyi WANG, Li LIU, Linghao MENG, Yuan MENG, Hanyue GUAN, Ning XU, Ning XIA   +7 more
doaj   +1 more source

Preventing disulfide bond formation weakens non-covalent forces among lysozyme aggregates. [PDF]

PLoS ONE, 2014
Nonnative disulfide bonds have been observed among protein aggregates in several diseases like amyotrophic lateral sclerosis, cataract and so on. The molecular mechanism by which formation of such bonds promotes protein aggregation is poorly understood ...
Vijay Kumar Ravi, Mohit Goel, Hema Chandra Kotamarthi, Sri Rama Koti Ainavarapu, Rajaram Swaminathan   +4 more
doaj   +1 more source

Halogen Bonding in Haspin-Halogenated Tubercidin Complexes: Molecular Dynamics and Quantum Chemical Calculations

Molecules, 2022
Haspin, an atypical serine/threonine protein kinase, is a potential target for cancer therapy. 5-iodotubercidin (5-iTU), an adenosine derivative, has been identified as a potent Haspin inhibitor in vitro.
Yujing Zhou, Ming Wah Wong
doaj   +1 more source

The World of Non-Covalent Interactions: 2006 [PDF]

Collection of Czechoslovak Chemical Communications, 2006
The review focusses on the fundamental importance of non-covalent interactions in nature by illustrating specific examples from chemistry, physics and the biosciences. Laser spectroscopic methods and both ab initio and molecular modelling procedures used for the study of non-covalent ...
Pavel Hobza, Rudolf Zahradník, Klaus Müller-Dethlefs   +2 more
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Understanding the non-covalent interaction mediated modulations on the electronic structure of quasi-zero-dimensional graphene nanoflakes

, 2018
Non-covalent interaction mediated controlled perturbations to the electronic properties of nanostructures as an alternative pathway for the non-destructive functionalization of graphene nanostructures.
Amrit Sarmah, Pavel Hobza
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Covalent polyphenols-proteins interactions in food processing: formation mechanisms, quantification methods, bioactive effects, and applications

Frontiers in Nutrition
Proteins and polyphenols are abundant in the daily diet of humans and their interactions influence, among other things, the texture, flavor, and bioaccessibility of food.
Kangyi Zhang, Kangyi Zhang, Kangyi Zhang, Jinbao Huang, Jinbao Huang, Jinbao Huang, Dongxu Wang, Xiaochun Wan, Yijun Wang, Yijun Wang, Yijun Wang   +10 more
doaj   +1 more source

A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity. [PDF]

PLoS ONE, 2010
Modification of proteins by the small ubiquitin like modifier (SUMO) is an essential process in mammalian cells. SUMO is covalently attached to lysines in target proteins via an enzymatic cascade which consists of E1 and E2, SUMO activating and ...
Jacqueline C Merrill, Tiffany A Melhuish, Michael H Kagey, Shen-Hsi Yang, Andrew D Sharrocks, David Wotton   +5 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source