Results 51 to 60 of about 346,816 (296)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Non-covalent Interactions

Citation: 'non-covalent interactions' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09875 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
Marcus Elstner, Qiang Cui, Maja Gruden
openaire   +2 more sources

Guanidinium and spermidinium decavanadates: as small biomimetic models to understand non-covalent interactions between decavanadate and arginine and lysine side chains in proteins

Frontiers in Chemical Biology
During the last three decades, numerous investigations have been conducted on polyoxidovanadates to treat several illnesses and inhibit enzymes. Numerous decavanadate compounds have been proposed as potential therapies for Diabetes mellitus, Cancer, and ...
Luis F. Paredes-Pérez, Angel Mendoza, Amalia García-García, Laura E. Serrano-De la Rosa, Miguel A. Méndez-Rojas, Francisco J. Melendez, María Eugenia Castro, Enrique González-Vergara   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Metal-Based Drug–DNA Interactions and Analytical Determination Methods

Molecules
DNA structure has many potential places where endogenous compounds and xenobiotics can bind. Therefore, xenobiotics bind along the sites of the nucleic acid with the aim of changing its structure, its genetic message, and, implicitly, its functions ...
Adriana Corina Hangan, Luminița Simona Oprean, Lucia Dican, Lucia Maria Procopciuc, Bogdan Sevastre, Roxana Liana Lucaciu   +5 more
doaj   +1 more source

Self-assembly of electroactive systems: from dimers to supramolecular polymers [PDF]

, 2018
Supramolecular aggregates and polymers are macromolecular entities that grow up by the non-covalent interaction of suitable monomeric units. In the search for new materials for optoelectronic applications through self-assembly, the control over the ...
Orti, Enrique
core  

A New Model of Chemical Bonding in Ionic Melts

, 2012
We developed a new physical model to predict macroscopic properties of inorganic molten systems using a realistic description of inter-atomic interactions.
Hess B., Oleg V. Prezhdo, Vitaly V. Chaban, Yuriy V. Pereverzev   +3 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The mechanism of pectin in improving anthocyanin stability and the application progress of their complexes: A review

Food Chemistry: X
Improving anthocyanin stability is a major challenge for the food industry. Studies have revealed that the interaction with pectin through non-covalent bonds can improve the anthocyanin stability, thus showing the potential to alleviate the above ...
Chenyang Shi, Chongting Guo, Shan Wang, Weixuan Li, Xue Zhang, Shan Lu, Chong Ning, Chang Tan   +7 more
doaj   +1 more source

Cold collisions of OH and Rb. I: the free collision [PDF]

, 2006
We have calculated elastic and state-resolved inelastic cross sections for cold and ultracold collisions in the Rb($^1 S$) + OH($^2 \Pi_{3/2}$) system, including fine-structure and hyperfine effects.
B. R. Johnson, D. M. Brink, Daniel E. Potter, H. J. Metcalf, I. Johansson, J. A. Coxon, J. P. Burke, Jeremy M. Hutson, John L. Bohn, Manuel Lara, N. F. Mott, Pavel Soldán, R. C. Forrey, R. D. Levine, R. D. Levine   +14 more
core   +2 more sources