Results 31 to 40 of about 19,819 (247)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

On the solvability of a boundary value problem for a two-dimensional system of Navier-Stokes equations in a cone

Қарағанды университетінің хабаршысы. Математика сериясы
Due to the fact that the Navier-Stokes equations are involved in the formulation of a large number of interesting problems that are important from an applied point of view, these equations have been the object of attention of mechanics, mathematicians ...
M.T. Jenaliyev, A.M. Serik, M.G. Yergaliyev   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

On a Problem Connected with Navier-stokes Equations in Non Cylindrical Domains

Journal of Mathematics and Statistics, 2005
Summary: We showed the existence of weak solutions of equations that represent flows of a non-homogeneous viscous incompressible fluids in a non cylindrical domain in \(\mathbb R^3\). The classical Navier-Stokes equation is a particular case of the equations here considered.
Limaco, J., De Menezes, S. B., Vaz, C., Montenegro, J. F   +3 more
openaire   +2 more sources

The Impact of High‐Productivity Processing on the Fatigue Failure of an Additive Manufactured Superalloy HAYNES 282

Advanced Engineering Materials, EarlyView.
The low cycle fatigue life of additive manufactured HAYNES® 282® superalloy was investigated for conventional and high‐productivity processing: samples of the former lasted 1400–1700 cycles, while samples of the latter failed at ~ 1200 cycles, at 760 °C and 1% strain.
Abdul Shaafi Shaikh, Ahmed Fardan, Tatiana Mishurova, Eduard Hryha   +3 more
wiley   +1 more source

Pullback attractors for a semilinear heat equation in a non-cylindrical domain

Journal of Differential Equations, 2008
The existence and uniqueness of a variational solution satisfying energy equality is proved for a semilinear heat equation in a non-cylindrical domain with homogeneous Dirichlet boundary condition, under the assumption that the spatial domains are bounded and increase with time.
Kloeden, Peter E., Marín Rubio, Pedro, Real Anguas, José   +2 more
openaire   +3 more sources

Laser Powder Bed Fusion of Copper–Tungsten Composites for Heat Sink Applications in High‐Power Electronics

Advanced Engineering Materials, EarlyView.
This article demonstrates the successful qualification of a copper–tungsten composite for laser powder bed fusion. The resulting components exhibited high density, high thermal conductivity, and reduced thermal expansion. Heat sinks with complex geometries were successfully manufactured, clearly showcasing the material's potential for additive ...
Simon Rauh, Shashank Deepak Prabhu, Jannik Huber, Lioba Fischer, Gerhard Wolf, Nico Hempel, Peter Mayr   +6 more
wiley   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Physically Based Model for Extracting Dual-Permeability Parameters Using Non-Newtonian Fluids

Vadose Zone Journal, 2019
Dual-permeability models simulate flow and transport within soils characterized by preferential (macro) and matrix (micro) pore domains, with each exhibiting distinct hydraulic properties.
Christelle N. Basset, Majdi R. Abou Najm, Ashtarout Ammar, Ryan D. Stewart, Scott C. Hauswirth, Georges Saad   +5 more
doaj   +1 more source

The wave equation with locally distributed control in non-cylindrical domain [PDF]

Boundary Value Problems, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources