Results 21 to 30 of about 2,276 (217)

Microwire-Based Sensor Array for Measuring Wheel Loads of Vehicles

open access: yesSensors, 2019
In this paper, a magnetic microwire-based sensor array embedded under the pavement is proposed as a weighing system at customs ports of entry. This sensor is made of a cementitious material suitable for embedding within the core of concrete structures ...
Jesus Olivera   +7 more
doaj   +1 more source

A Generalized Method for In-Process Defect Detection in Friction Stir Welding

open access: yesJournal of Manufacturing and Materials Processing, 2022
Friction stir welding (FSW) is an advantageous solid-state joining process that is suitable for many materials in multiple industries. In an industrial setting, manufacturers are actively seeking faster welding speeds to increase throughput.
Johnathon B. Hunt   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Simulation-assisted multimodal deep learning (Sim-MDL) fusion models for the evaluation of thermal barrier coatings using infrared thermography and Terahertz imaging

open access: yesScientific Reports
Thermal Barrier Coatings (TBCs) are critical for high-temperature applications, such as gas turbines and aerospace engines, protecting metallic substrates from extreme thermal stress and degradation.
Sruthi Krishna Kunji Purayil   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Near-Infrared Spectroscopy for Rapid Determination of Physicochemical Properties of Fermented Fish Sauce (‘Nam Pla-Ra’)

open access: yesFood Technology and Biotechnology
Research background. Thai community product quality standards have been established for nam pla-ra, which require at least 4 % protein and 12 % sodium chloride. Determining the protein and NaCl contents requires chemicals and is time-consuming.
Sunee Jungtheerapanich   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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