Results 31 to 40 of about 453,542 (260)
Scientific ReportsThermal Barrier Coatings (TBCs) are critical for high-temperature applications, such as gas turbines and aerospace engines, protecting metallic substrates from extreme thermal stress and degradation.
Sruthi Krishna Kunji Purayil +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Autonomous Robotic System using Non-Destructive Evaluation methods for Bridge Deck Inspection
, 2017 Bridge condition assessment is important to maintain the quality of highway roads for public transport. Bridge deterioration with time is inevitable due to aging material, environmental wear and in some cases, inadequate maintenance.
Berendsen, Tony +4 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Non-destructive methods for fruit quality evaluation
Scientific Reports, 2021 This work studies the evolution in time of several varieties of apples with application in quality storage maintenance. Two different methods were used to evaluate long-stored apples for better sorting and degradation assessment.
Ana-Maria Bratu +4 more
doaj +1 more source
Non-Destructive Inspection of Impact Damage in Composite Aircraft Panels by Ultrasonic Guided Waves and Statistical Processing. [PDF]
, 2017 This paper discusses a non-destructive evaluation (NDE) technique for the detection of damage in composite aircraft structures following high energy wide area blunt impact (HEWABI) from ground service equipment (GSE), such as heavy cargo loaders and ...
Capriotti, Margherita +3 more
core +2 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Evaluation of recycled concrete by means of non destructive tests
Materiales de Construccion, 2003 The use of recycled concrete as aggregate for the production of new concretes is a consequence of the shortage of natural resources and the environmental problems due to the storage of residual building materials.
A. A. Di Maio, L. P. Traversa
doaj +1 more source
Evaluating subsurface damage in optical glasses [PDF]
Journal of the European Optical Society-Rapid Publications, 2011 Hard brittle materials (e.g. glasses and ceramics) increasingly appeal to general interests because of their excellent physical, mechanical and chemical properties such as super hardness and strength at extreme temperature and chemical stability.
Wang Jian +4 more
doaj +1 more source