Results 41 to 50 of about 453,542 (260)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Green Energy and Intelligent TransportationRailroad condition monitoring is paramount due to frequent passage through densely populated regions. This significance arises from the potential consequences of accidents such as train derailments, hazardous materials leaks, or collisions which may have
Md Arifur Rahman +2 more
doaj +1 more source
A Robust Approach to Optimal Matched Filter Design in Ultrasonic Non-Destructive Evaluation (NDE) [PDF]
, 2016 The matched filter was demonstrated to be a powerful yet efficient technique to enhance defect detection and imaging in ultrasonic non-destructive evaluation (NDE) of coarse grain materials, provided that the filter was properly designed and optimized ...
Hayward, Gordon, Li, Minghui
core +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Bridge inspection practices using non-destructive testing methods
Journal of Civil Engineering and Management, 2015 Non-Destructive Testing (NDT) methods have been developed and employed as a means of rapid and effective structural inspection. Despite the various kinds of NDT methods developed for bridge inspection, not much study has been performed on their usage and
Sangwook Lee, Nikolas Kalos
doaj +1 more source
Non-Destructive Testing Applications for Steel Bridges
Applied Sciences, 2021 The growing population and increasing demand for surface transportation have highlighted the importance of maintaining safe and reliable civil infrastructures for daily use.
Seyed Saman Khedmatgozar Dolati +3 more
doaj +1 more source
Optical non-destructive evaluation of articular cartilage integrity: A review [PDF]
, 2011 This paper reviews the current status of the application of optical non-destructive methods, particularly infrared (IR) and near infrared (NIR), in the evaluation of the physiological integrity of articular cartilage.
Afara, Isaac +2 more
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Multiplexed SQUID array for non-destructive evaluation of aircraft structures [PDF]
, 2000 SQUID sensors offer a significant advantage for eddy-current (EC) testing of aircraft components for material flaws hidden deeply in the tested structure. However, the requirement to take maps of the magnetic field, usually by meander-shaped scans, leads
Gärtner, S. +9 more
core +1 more source