Results 51 to 60 of about 562,651 (301)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
A review of non-destructive testing using robot [PDF]
MATEC Web of ConferencesWith the wide application of new materials, new structures, and new technology in modern industry especially in the aerospace industry, the range of non-destructive testing has not been limited on normal materials or normal shapes, the test of complex ...
Lin Yongqian +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
International Journal of Food PropertiesFor decades researches have been conducted in Ethiopia to improve wheat productivity and quality. This involved extensive selection of breeding lines based on agronomic and laboratory data from numerous trials. However, generating laboratory data for all
Yadesa Abeshu, Cherinet Kasahun
doaj +1 more source
Monitoring of Changes Signal Acoustic Emission Signals Using Waveguides
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017 This paper is focused on possibilities of acoustic emission (AE) signal detection from material surface through waveguide for commonly used piezoelectric sensors.
Jaroslav Začal +3 more
doaj +1 more source
Sensing physical stage of fruits by their response to non destructive impacts. [PDF]
, 1992 Fruits of two varieties of both apples and pears were tested in the laboratory to measure their response to a small energy impact applied by an impact tester. Samples of fruits of increasing maturity were tested during several weeks.
Jaren Ceballos, Carmen +2 more
core
Influence of welding passes on grain orientation - The example of a multi-pass V-weld [PDF]
, 2012 International audienceThe accurate modelling of grain orientations in a weld is important, when accurate ultrasonic test predictions of a welded assembly are needed.
Chassignole, Bertrand +6 more
core +3 more sources