Results 181 to 190 of about 157,420 (243)

Clinical Trial: Lemborexant Efficacy and Safety in Liver Cirrhosis—Randomized, Double‐Blind, Crossover Clinical Trial

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 458-470, August 2026.
RESTORE is a prospective, double‐blind, placebo‐controlled, crossover trial evaluating Lemborexant in cirrhosis at Cipto Mangunkusumo National Referral Hospital. Both 5 and 10 mg doses reduced PSQI by week 2, with sustained benefits post‐crossover. The 5 mg group improved Stroop Test performance, whereas the 10 mg group had prolonged reaction time ...
Rino Alvani Gani, Pitt Akbar, Irsan Hasan, Andri Sanityoso Sulaiman, Cosmas Rinaldi Adithya Lesmana, Juferdy Kurniawan, Sarah Melissa Panjaitan, Valerie Josephine Dirjayanto   +7 more
wiley   +1 more source

Mechanisms of action of polyhexamethylene biguanide-based biocides against non-enveloped virus [PDF]

Human viral pathogens place a serious threat on the healthcare system. Adequate and efficient disinfection procedures minimise the incidence of surface contamination and viral disease transmission. Biocide type, environmental conditions and viral characteristics e.g. presence of envelope influence the disinfection effectiveness. Thus, understanding the
openaire  

Impact of ABO Blood System on Immunogenicity and Vaccine Efficacy of COVID‐19 Booster Vaccination—A Population‐Based Study of 3066 Individuals

Influenza and Other Respiratory Viruses, Volume 20, Issue 8, August 2026.
ABSTRACT Background ABO blood group has been associated with SARS‐CoV‐2 susceptibility. Little data exist regarding the impact of ABO and Rhesus (Rh[D]) type on breakthrough infections and antibody responses following SARS‐CoV‐2 booster vaccination. Methods This multicenter, population‐based cohort study includes individuals ≥ 18 years who received a ...
Daniela Sieghart, Galateja Jordakieva, Caroline Dürrschmid, Claudia A. Hana, Lan Vi Tran, Leonhard X. Heinz, Helmuth Haslacher, Markus Zlesak, Valentin Marzoner, Philip Nasztl, Giulia Piccini, Alessandro Manenti, Emanuele Montomoli, Anselm Jorda, Clemens Fedrizzi, Timothy Hasenoehrl, Andrej Zdravkovic, Karolina Anderle, Ursula Wiedermann, Susanne Drapalik, Helmut Steinbrecher, Felix Bergmann, Christa Firbas, Barbara Wagner, Margherita Leonardi, Giulio Pierleoni, Matilde Ballini, Linda Benincasa, Serena Marchi, Claudia Maria Trombetta, Thomas Perkmann, Richard Crevenna, Markus Zeitlinger, Michael Bonelli, Daniel Aletaha, Helga Radner   +35 more
wiley   +1 more source

Development and Validation of a Viability RT‐qPCR Assay for Detecting Infectious Spring Viraemia of Carp Virus (SVCV)

Journal of Fish Diseases, Volume 49, Issue 8, August 2026.
ABSTRACT Spring viremia of carp virus (SVCV) is a contagious pathogen associated with significant mortality and economic losses in freshwater aquaculture. Although reverse transcription quantitative PCR (RT‐qPCR) enables rapid detection, it does not distinguish between infectious and non‐infectious viral particles, which may lead to overestimation of ...
Ha‐Jeong Son, Min‐Young Sohn, Jae‐Ok Kim, Hee Jung Choi, Mun‐Gyeong Kwon, Jeong‐Tae Lee, Gyoungsik Kang, HyeongJin Roh, Chan‐Il Park, Kyung‐Ho Kim   +9 more
wiley   +1 more source

TAM receptor tyrosine kinases as potential mediators of the non-lytic spread of non-enveloped viruses. [PDF]

Biochem Soc Trans
Moran SJ, Starbird CA.
europepmc   +1 more source

Non-enveloped virus infection probed with host cellular molecules : a structural study

, 2002
Early steps in virus replication require binding of the virus to its target cell, entry into the cell, and delivery of the viral genome into the cell in order to gain access to the cellular macromolecular synthesis machinery. This infectious process can only be initiated if the virus successfully attaches to a specific receptor on the plasma membrane ...
openaire   +1 more source

Identification and Optimization of a Truncated Hs‐1‐Derived Antimicrobial Peptide for Enhanced Broad‐Spectrum Antiviral Activity

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Can a shorter peptide be a better antiviral? Structure‐guided optimization of the amphibian peptide Hs‐1 reveals a minimal α‐helical core that, after terminal modification, displays enhanced stability and submicromolar broad‐spectrum activity against enveloped viruses while maintaining a favorable safety profile. Antimicrobial peptides (AMPs) represent
Carla Zannella, Annalisa Chianese, Rosa Giugliano, Roberta Della Marca, Alessandra Monti, Martina Dragone, Gaetano Malgieri, Nunzianna Doti, Carla Isernia, Anna De Filippis, Massimiliano Galdiero   +10 more
wiley   +1 more source

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato, Giacomo Bettin, Chiara Dalla Torre, Lorenzo Stella, Marta De Zotti   +4 more
wiley   +1 more source

ICTV Virus Taxonomy Profile: <i>Rhabdoviridae</i> 2026. [PDF]

J Gen Virol
Walker PJ, Bejerman N, Blasdell KR, Debat H, Dietzgen RG, Fooks AR, Freitas-Astúa J, Garver K, Kondo H, Ramos-González PL, Shi M, Tesh RB, Tordo N, Vasilakis N, Whitfield AE.   +14 more
europepmc   +1 more source

Glycol vapor pathogen disinfection: a defensive technology for emerging biothreats. [PDF]

Front Microbiol
Siddiqui S, Pannu J.
europepmc   +1 more source