Results 71 to 80 of about 292,242 (199)
Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development. [PDF]
, 2019 Cytomegalovirus (CMV) infection causes birth defects and life-threatening complications in immunosuppressed patients. Lack of vaccine and need for more effective drugs have driven widespread ongoing therapeutic development efforts against human CMV (HCMV)
Balogun, Rilwan +9 more
core +2 more sources
Egress of non-enveloped enteric RNA viruses
Journal of General Virology, 2021 A long-standing paradigm in virology was that non-enveloped viruses induce cell lysis to release progeny virions. However, emerging evidence indicates that some non-enveloped viruses exit cells without inducing cell lysis, while others engage both lytic ...
I. Owusu +3 more
semanticscholar +1 more source
Virus Infection Recognition and Early Innate Responses to Non-Enveloped Viral Vectors [PDF]
Viruses, 2010 Numerous human genetic and acquired diseases could be corrected or ameliorated if viruses are harnessed to safely and effectively deliver therapeutic genes to diseased cells and tissues in vivo. Innate immune and inflammatory response represents one of the key stumbling blocks during the development of viral-based therapies.
openaire +3 more sources
Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses
eLife, 2019 Many ‘non-enveloped’ viruses, including hepatitis A virus (HAV), are released non-lytically from infected cells as infectious, quasi-enveloped virions cloaked in host membranes.
Efraín E Rivera-Serrano +3 more
doaj +1 more source
Capture and inactivation of viral particles from bioaerosols by electrostatic precipitation
iScience, 2023 Summary: Infectious viral particles in bioaerosols generated during laparoscopic surgery place staff and patients at significant risk of infection and contributed to the postponement of countless surgical procedures during the COVID-19 pandemic causing ...
Hannah E. Preston +5 more
doaj +1 more source
Atomic model of a non-enveloped virus reveals pH sensors for a coordinated process of cell entry
Nature Structural &Molecular Biology, 2015 Viruses sense environmental cues such as pH to engage in membrane interactions for cell entry during infection, but how nonenveloped viruses sense pH is largely undefined.
Xing Zhang +6 more
semanticscholar +1 more source
Viruses, 2022 Virus-based biopharmaceutical products are used in clinical applications such as vaccines, gene therapy, and immunotherapy. However, their manufacturing remains a challenge, hampered by the lack of appropriate analytical tools for purification monitoring
Rita P. Fernandes +8 more
semanticscholar +1 more source
Dependence of ethanol effects on protein charges [PDF]
, 2014 Ethanol is used as a conventional disinfectant solution. It is highly effective against enveloped viruses due to its effects on virus membranes. It also confers inactivation of non-enveloped viruses, which can be ascribed to conformational changes or ...
Arakawa Tsutomu +3 more
core +1 more source
AboutOpenIntroduction: Alcohol-based hand sanitizers are used in healthcare settings, but their efficacy against both enveloped and non-enveloped viruses requires further investigation.
Claudio Cermelli +5 more
doaj +1 more source
Journal of Microbiology, Immunology and Infection, 2022 Background: In Taiwan, there were only 799 confirmed COVID-19 cases in 2020. The unique backdrop amidst a pandemic and promotion of nonpharmaceutical interventions generated some distinct changes in the epidemiology of common respiratory pathogens.
Jun Yi Sim +10 more
doaj +1 more source