Results 31 to 40 of about 35,137 (259)

Modeling Non-Equilibrium Dynamics of a Discrete Probability Distribution: General Rate Equation for Maximal Entropy Generation in a Maximum-Entropy Landscape with Time-Dependent Constraints

open access: yesEntropy, 2008
A rate equation for a discrete probability distribution is discussed as a route to describe smooth relaxation towards the maximum entropy distribution compatible at all times with one or more linear constraints. The resulting dynamics follows the path of
Gian Paolo Beretta
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Entropy, Extropy and the Physical Driver of Irreversibility [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2012
We point out that the fundamental irreversibility of Nature requires the introduction of a suitable measure for the distance from equilibrium. We show that entropy, which is widely held to be such a measure, suffers from the problem that it does not have
Attila Grandpierre
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Partition Function and Configurational Entropy in Non-Equilibrium States: A New Theoretical Model

open access: yesEntropy, 2018
A new model of non-equilibrium thermodynamic states has been investigated on the basis of the fact that all thermodynamic variables can be derived from partition functions.
Akira Takada   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Multidimensional thermodynamic potential for descriptions of ultrathin lubricant film melting between two atomically smooth surfaces

open access: yesCondensed Matter Physics, 2011
The thermodynamic model of ultrathin lubricant film melting, confined between two atomically-flat solid surfaces, is built using the Landau phase transition approach. Non-equilibrium entropy is introduced describing the part of thermal motion conditioned
I.A. Lyashenko   +2 more
doaj   +1 more source

The Second Law and Entropy Misconceptions Demystified

open access: yesEntropy, 2020
The challenges and claims of hypothetical violations of the Second Law of thermodynamics have been a topic of many scientific, philosophical and social publications, even in the most prestigious scientific journals.
Milivoje M. Kostic
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Thermodynamic Measure for Nonequilibrium Processes [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2007
One of the most fundamental laws of Nature is formulated by the Second Law of Thermodynamics. At present, in its usual formulation the central concept is entropy characterized in terms of equilibrium state variables.
Attila Grandpierre, Katalin Martinás
doaj  

Home - About - Disclaimer - Privacy