Results 51 to 60 of about 10,879,472 (249)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Entanglement spreading in non-equilibrium integrable systems
SciPost Physics Lecture Notes, 2020 These are lecture notes for a short course given at the Les Houches Summer School on ``Integrability in Atomic and Condensed Matter Physics'', in summer 2018.
Pasquale Calabrese
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Is There a Unique Physical Entropy? Micro versus Macro [PDF]
, 2012 Entropy in thermodynamics is an extensive quantity, whereas standard methods in statistical mechanics give rise to a non-extensive expression for the entropy. This discrepancy is often seen as a sign that basic formulas of statistical mechanics should be
Dieks, D.G.B.J. +4 more
core +1 more source
Coarse-graining and entropy production out of equilibrium [PDF]
, 2022 The problem of establishing how different coarse-graining procedures affect the law of generalized detailed balance and the rate of entropy production is addressed in the context of different models describing systems in stationary states out of ...
Sanson, Riccardo
core
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Atti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2019 From a new rigorous formulation of the general axiomatic foundations of thermodynamics we derive an operational definition of entropy that responds to the emergent need in many technological frameworks to understand and deploy thermodynamic entropy well ...
Gian Paolo Beretta, Enzo Zanchini
doaj +1 more source
Maximum entropy production principle in forest dynamics modelling [PDF]
BIO Web of ConferencesForest ecosystems are vivid representatives of open non-equilibrium systems. The existence of extreme principles in “ecological thermodynamics” is a subject of discussion in the works of many physicists, ecologists and researchers dealing with non ...
Lisitsyn Viktor +3 more
doaj +1 more source