Results 131 to 140 of about 3,467,784 (263)

Non-Essential Amino Acid Availability Influences Proteostasis and Breast Cancer Cell Survival During Proteotoxic Stress. [PDF]

Mol Cancer Res, 2023
Sannino S, Manuel AM, Shang C, Wendell SG, Wipf P, Brodsky JL.   +5 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Correction to: Associations of Essential and Non-Essential Trace Elements' Levels in the Blood, Serum, and Urine in Women with Premature Ovarian Insufficiency. [PDF]

Biol Trace Elem Res
Kek T, Geršak K, Kuželički NK, Šturm DC, Mazej D, Tratnik JS, Falnoga I, Horvat M, Virant-Klun I.   +8 more
europepmc   +1 more source

Arabidopsis-expressing lysine-null SUMO1 reveals a non-essential role for secondary SUMO modifications in plants. [PDF]

Plant Direct, 2023
Rytz TC, Feng J, Barros JAS, Vierstra RD.   +3 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Exposure and Health Impact Assessment of Essential and Non-essential Elements in Rice Sold on Ghanaian Markets. [PDF]

Environ Health Insights
Awewomom J, Arhin TY, Takyi YD, Gyasi Yaw A, Saaka J, Opoku F, Tandoh MA, Amankwah EA, Akoto O.   +8 more
europepmc   +1 more source

In fission yeast, 65 non-essential mitochondrial proteins related to respiration and stress become essential in low-glucose conditions. [PDF]

R Soc Open Sci, 2023
Mori A, Uehara L, Toyoda Y, Masuda F, Soejima S, Saitoh S, Yanagida M.   +6 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Etiology of non-typical suicide patterns essential

Indian Journal of Public Health, 2013
Thomas Iain Lemon
doaj   +1 more source

Are taxes to sugar-sweetened beverages and non-essential energy dense food implemented in Mexico regressive? [PDF]

PLoS One
Quiroz-Reyes JA, Morales-Ríos JE, Vargas-Flores A, Sánchez-Ortiz NA, Colchero MA.   +4 more
europepmc   +1 more source