Results 71 to 80 of about 469,292 (261)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A Review of Non-Functional Requirements Analysis Throughout the SDLC

Computers
To date, unquestionable efforts have been made, both in academia and industry, to facilitate the development of functional requirements (FRs) throughout the different phases of the software development life cycle (SDLC).
Cyrille Dongmo
doaj   +1 more source

Requirements Engineering Contributions on the Development of Educational Software for the Blind or People with Impaired Vision

CLEI Electronic Journal, 2006
This paper presents an account of the experience observed when obtaining a set of requirements for the development of educational software for people with impaired vision.
Victor Francisco Araya Santander, Dorisvaldo Rodrigues da Silva   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Functional and Non-Functional Requirements of a Telemedicine System for Chronic Pain Management [PDF]

مجله انفورماتیک سلامت و زیست پزشکی
Introduction: With the expansion of information and communication technologies, telemedicine systems have become a key tool in enhancing the quality of healthcare services.
Zeinab Kohzadi, Ali Dabbagh, Mehrdad Taheri, Hassan Emami, Mahshid Ghasemi, Zahra Kohzadi, Shahabedin Rahmatizadeh   +6 more
doaj  

Toward Empirically Investigating Non-Functional Requirements of iOS Developers on Stack Overflow

IEEE Access, 2019
Context: Mobile application developers are getting more concerned due to the importance of quality requirements or non-functional requirements (NFR) in software quality.
Arshad Ahmad, Chong Feng, Kan Li, Syed Mohammad Asim, Tingting Sun   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Enhancing Software Sustainability: Leveraging Large Language Models to Evaluate Security Requirements Fulfillment in Requirements Engineering

Systems
In the digital era, cybersecurity is integral for preserving national security, digital privacy, and social sustainability. This research emphasizes the role of non-functional equirements (NFRs) in developing secure software systems that enhance societal
Ahmad F. Subahi
doaj   +1 more source