Results 81 to 90 of about 512,511 (217)

Identifying Non-Functional Requirements From Unconstrained Documents Using Natural Language Processing and Machine Learning Approaches

IEEE Access
Requirements engineering is the first phase in software development life cycle and it also plays one of the most important and critical roles. Requirement document mainly contains both functional requirements and non-functional requirements.
Qais A. Shreda, Abualsoud A. Hanani
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The efficiency of machine learning algorithms in classifying non-functional requirements

New Trends in Computer Sciences
Machine learning (ML) algorithms are more and more widely applied in various types of systems, so the research related to them is also increasing. One of the areas of research under consideration is the classification of non-functional requirements ...
Milda Maciejauskaitė, Jolanta Miliauskaitė   +1 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

FRUIT: Fuzzy Representation of Unbounded and Imprecise Terms in Non-Functional Requirements

IEEE Access
It is challenging to verify Non-Functional Requirements (NFRs) because the traditional verification process typically uses the binary concept of true or false to determine whether a requirement has been fulfilled, leaving no space for uncertainty, even ...
Franklin Parrales-Bravo, Rosangela Caicedo-Quiroz, Julio Barzola-Monteses, Leonel Vasquez-Cevallos   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

An Architecture Assessment Model: Holistic Evaluation of Software Architecture

IEEE Access
Current architecture review methods predominantly focus on verifying compliance between design and requirements, as well as between code and design. However, they often overlook whether the final product has been adequately tested against architecturally
Mujdat Bayar, Onur Taviloglu, Ahmet Unudulmaz, Yavuz Gunes, Koray Dogutekin   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Automated Classification and Identification of Non-Functional Requirements in Agile-Based Requirements Using Pre-Trained Language Models

IEEE Access
Non-functional requirements (NFRs) are critical factors for software quality and success. A frequently reported challenge in agile requirements engineering is that NFRs are often neglected due to the focus on functional requirements (FRs) and the limited
Abdulrahim Alhaizaey, Majed Al-Mashari
doaj   +1 more source