Results 81 to 90 of about 22,410,258 (325)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Biasing and the search for primordial non-Gaussianity beyond the local type [PDF]
, 2016 Primordial non-Gaussianity encodes valuable information about the physics of inflation, including the spectrum of particles and interactions. Significant improvements in our understanding of non-Gaussanity beyond Planck require information from large ...
J. Gleyzes +3 more
semanticscholar +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Flattened bispectrum of the scalar-induced gravitational waves
European Physical Journal C: Particles and FieldsRecent pulsar timing array collaborations have reported evidence of the stochastic gravitational wave background. The gravitational waves induced by primordial curvature perturbations, referred to as scalar-induced gravitational waves (SIGWs), could ...
Qing-Hua Zhu
doaj +1 more source
CMB B -mode non-Gaussianity [PDF]
, 2016 We study the degree to which the cosmic microwave background (CMB) can be used to constrain primordial non-Gaussianity involving one tensor and two scalar fluctuations, focusing on the correlation of one polarization $B$ mode with two temperature modes ...
P. Meerburg +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Deciphering non-Gaussianity of diffusion based on the evolution of diffusivity
Physical Review ResearchNon-Gaussian diffusion of nanoparticles in complex media disrupts Einstein's picture of Brownian motion, and non-Gaussianity is thought to be closely related to diffusing diffusivity generated by spatiotemporal heterogeneities.
Haolan Xu, Xu Zheng, Xinghua Shi
doaj +1 more source
Galaxy bias and primordial non-Gaussianity [PDF]
, 2015 We present a systematic study of galaxy biasing in the presence of primordial non-Gaussianity. For a large class of non-Gaussian initial conditions, we define a general bias expansion and prove that it is closed under renormalization, thereby showing ...
Valentin Assassi, D. Baumann, F. Schmidt
semanticscholar +1 more source
Non-Gaussianity in island cosmology [PDF]
Physical Review D, 2009 5 pages, 1 eps figure, some discussions added, published ...
openaire +2 more sources
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source