Results 31 to 40 of about 681,503 (293)
Challenges and Opportunities of Non-governmental Organizations
Non-governmental organizations play an extremely important role in society, intervening subsidiarily for the welfare of society.This paper describes the results of an exploratory qualitative research, the ...
Diana C. Bodi
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Non-Economic Factors Affecting Employment in Non-Governmental Organizations
Subject and purpose of work: The aim of the paper is to identify non-economic factors influencing employment in non-governmental organizations in the Subcarpathian Province.
Frączek Piotr, Pater Patrycja
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Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
In the 21st century, non-governmental organizations play an increasingly important role in international relations, and their considerable advancement is crucial in solving many global problems, especially those specialized in environmental or human ...
Stefan Gheorghe
doaj
Project Management in Development Cooperation. Non-Governmental Organizations
This article analyzes the adoption of project management practices in development cooperation NGOs and their influence on project performance. This paper illustrates the impact in the implementation of methodologies, techniques and tools on outcomes ...
Maricela I. Montes-Guerra +4 more
doaj +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Kate Hanson Professor of Community Leadership, travels to Thailand [PDF]
Professor Hanson travelled to Thailand to visit non-governmental organizations and to explore possibilities for partnerships with her program/UNH ...
Hanson, Kate
core +2 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

