Results 41 to 50 of about 686,551 (292)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Non-governmental organizations and multi-sited marine conservation science: A case study [PDF]

, 2010
Non-governmental organizations (NGOs) are now major players in the realm of environmental conservation. While many environmental NGOs started as national organizations focused around single-species protection, governmental advocacy, and preservation of
Hastings, Jesse
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Donors’ Participation the Health System: A Double-Edged Sword [PDF]

Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat
The presence of donors in health system, despite its positive results, can also have weaknesses that sometimes act as a double-edged sword in achieving health priorities. In some cases, the needs are considered by donors as unnecessarily the real ones in
khatere khanjankhani, seyede maryam najibi   +1 more
doaj  

Religious non-governmental organizations and philanthropy in Indonesia

Indonesian Journal of Islam and Muslim Societies, 2013
Religious non-governmental organizations (RNGOs) and philanthropic activities in Indonesia have a long history. They existed prior to the creation of the nation state. Social, political and economic changes in this country have influenced the development
Tuti Alawiyah
doaj   +1 more source

Engaging Local Non-Governmental Organizations (NGOs) in the Response to HIV/AIDS. [PDF]

, 2005
During the past few years, a number of key donor programs have scaled up their global response to the crisis of HIV and AIDS. The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM), the World Health Organization (WHO), the Joint United Nations ...
Cornman, Helen, Grimm, Curt D., Rana, Sujata   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The Resources and Governance of Non-Governmental Organizations in Uganda [PDF]

Using original survey data, we document the activities, resources, and governance structure of NGOs operating in Uganda. The NGO sector is funded primarily by international non-governmental organizations and bilateral donors.
Abigail Barr, Marcel Fafchamps, Trudy Owens   +2 more
core   +3 more sources

Non-governmental Organizations and Construction of Social Problems: An Ethnographic Study of Non-Governmental Organizations in Sardasht [PDF]

مسائل اجتماعی ایران
The emergence of non-governmental organizations in Sardasht is tied to the diversity and intensification of social problems. This research analyzes the experiences of Sardasht non-governmental organizations in the construction of social problems within ...
Omid Ghaderzadeh, Rahmat Foroughi
doaj