Results 31 to 40 of about 11,410,717 (272)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

ANALYZING THE CAPABILITIES OF NON-GOVERNMENTAL ORGANIZATIONS TO ACHIEVE THE PRINCIPLES OF GOOD GOVERNANCE A CASE STUDY OF SOME NON-GOVERNMENTAL ORGANIZATIONS IN SHARKIA GOVERNORATE [PDF]

Fayoum Journal of Agricultural Research and Development, 2020
The efforts of the NGOs in Egypt are based on a fundamental axis that is mobilizing the efforts of individuals and associations to bring about development in society for the benefit of these individuals and groups, solving their problems and contributing
ElBasiony Mohamed Elsaid
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Non-Economic Factors Affecting Employment in Non-Governmental Organizations

Studia Ekonomiczne i Regionalne, 2018
Subject and purpose of work: The aim of the paper is to identify non-economic factors influencing employment in non-governmental organizations in the Subcarpathian Province.
Frączek Piotr, Pater Patrycja
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

'Post-1994 challenges facing South African NGOs : a case study of six Western Cape Non-Governmental Organizations that have a development focus' [PDF]

, 2010
Includes bibliographical references (leaves 92-104).This study examines post-1994 challenges facing six Western Cape NGOs with a development focus in South Africa.
Chimangafisi, Lemekeza
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

PROBLEMS OF RISK COMMUNICATION: NON-GOVERNMENTAL ORGANIZATIONS AND THEIR ROLE IN THE DEVELOPMENT OF THE PUBLIC OPINION ON ISSUES OF POPULATION’S RADIATION PROTECTION

Радиационная гигиена, 2018
Events connected with the development and improvement of the nuclear industry are usually ambiguously perceived by the public. Mass-media and Internet play a leading role in the development of the public opinion on the most relevant public life issues ...
A. M. Biblin, N. M. Vishnyakova, K. V. Varfolomeeva, S. A. Zelentsova, E. V. Khramtsov, R. R. Akhmatdinov   +5 more
doaj   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Project Management in Development Cooperation. Non-Governmental Organizations

Innovar: Revista de Ciencias Administrativas y Sociales, 2015
This article analyzes the adoption of project management practices in development cooperation NGOs and their influence on project performance. This paper illustrates the impact in the implementation of methodologies, techniques and tools on outcomes ...
Maricela I. Montes-Guerra, Aida R. De-Miguel, M. Amaya Pérez-Ezcurdia, Faustino N. Gimena Ramos, H. Mauricio Díez-Silva   +4 more
doaj   +1 more source