Results 81 to 90 of about 12,537,270 (248)

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

Colesterol total e colesterol das lipoproteinas de alta densidade em doentes com diabetes mellitus nao insulinodependente.

Acta Médica Portuguesa, 1995
Non-insulin-dependent diabetics often have quantitative changes in plasma lipid profiles characterised by higher triglycerides and lower HDL-cholesterol than the average population.
C M Dias, P Nogueira, A V Rosa, J V De Sa, M F Gouvea, J C Marinho Falcao   +5 more
doaj   +1 more source

Blood cholesterol levels of hypercholesterolemic rat (Rattus norvegicus) after VCO treatment [PDF]

, 2009
Abstrak. Harini M, Astirin OP. 2009. Kadar kolesterol darah tikus putih (Rattus norvegicus) hiperkolesterolemik setelah perlakuan VCO. Nusantara Bioscience 1: 53-58.
ASTIRIN, OKID PARAMA, HARINI, MARTI
core  

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source

Therapeutic approaches to raising plasma HDL-cholesterol levels

, 2004
Epidemiologic data from the Framingham and Prospective Cardiovascular Munster studies, demonstrating an inverse correlation between the plasma concentration of HDLs and the incidence of cardiovascular disease, have driven research to explore precisely ...
Thompson, M., Reed, S.C., Cockerill, G.
core   +1 more source

New therapeutic options for metabolic‐associated steatotic liver disease

British Journal of Clinical Pharmacology, EarlyView.
An increasing number of patients are being diagnosed with metabolic dysfunction‐associated steatotic liver disease (MASLD). MASLD results from disturbances in hepatic lipid metabolism and is associated with an increased risk of cirrhosis and hepatocellular carcinoma and significant extrahepatic morbidity, including cardiovascular disease and ...
Tessa Straatmijer, Midas Mulder
wiley   +1 more source

Non-HDL-Cholesterol and Total Cholesterol to HDL-C Ratio in Abdominally Obese Adults in Phitsanulok

Siriraj Medical Journal, 2009
Objective: To compare non-HDLc and the TC/HDLc ratio in men and women with and without abdominal obesity (AO). To evaluate the association of non-HDLc and the TC/HDLc ratio with the other risk factors and to estimate the non-HDLc and TC/HDLc ratio level ...
Surapon Tangvarasittichai, Orathai Tangvarasittichai, Sirilak Teeraputon, Ratchaneewan Maneemaroj, Wanvisa Boonlert, Jirapas Jongjitwimol, Watchanan Wongseana, Panadda Jermsri, Suwadee Meemark, Nipaporn Sangaroon   +9 more
doaj  

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Effects of metformin versus sulfonylureas on atherogenic indices and cardiometabolic risk in type 2 diabetes mellitus

Endocrine and Metabolic Science
Introduction: Atherogenic dyslipidaemia is a common feature of type 2 diabetes mellitus (T2DM) and contributes substantially to increased cardiovascular risk.
Israa Qusay Falih, Hadeel Delman Najim, Noor Thair Tahir   +2 more
doaj   +1 more source