Results 51 to 60 of about 801,210 (251)

An Operator-Valued Kantorovich Metric on Complete Metric Spaces [PDF]

open access: yes, 2018
The Kantorovich metric provides a way of measuring the distance between two Borel probability measures on a metric space. This metric has a broad range of applications from bioinformatics to image processing, and is commonly linked to the optimal transport problem in computer science.
arxiv   +1 more source

Sharp uncertainty principles on metric measure spaces [PDF]

open access: yesarXiv, 2023
We study the Heisenberg-Pauli-Weyl uncertainty principle and the Caffarelli-Kohn-Nirenberg interpolation inequalities, on metric measure spaces satisfying measure contraction property. Using localization techniques, we show that these inequalities are valid only on volume cones.
arxiv  

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

open access: yesFEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law   +6 more
wiley   +1 more source

Permanence of metric fractals

open access: yesElectronic Journal of Differential Equations, 2007
The paper studies energy functionals on quasimetric spaces, defined by quadratic measure-valued Lagrangeans. This general model of medium, known as metric fractals, includes nested fractals and sub-Riemannian manifolds.
Kyril Tintarev
doaj  

Ramified optimal transportation in geodesic metric spaces [PDF]

open access: yesAdvances in Calculus of Variations , Volume 4 (3), (2011): 277-307, 2009
An optimal transport path may be viewed as a geodesic in the space of probability measures under a suitable family of metrics. This geodesic may exhibit a tree-shaped branching structure in many applications such as trees, blood vessels, draining and irrigation systems.
arxiv   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Enhanced dose prediction for head and neck cancer artificial intelligence‐driven radiotherapy based on transfer learning with limited training data

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Training deep learning dose prediction models for the latest cutting‐edge radiotherapy techniques, such as AI‐based nodal radiotherapy (AINRT) and Daily Adaptive AI‐based nodal radiotherapy (DA‐AINRT), is challenging due to limited data.
Hui‐Ju Wang   +5 more
wiley   +1 more source

Assessing proton plans with three different beam delivery systems versus photon plans for head and neck tumors

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare plan quality among photon volumetric modulated arc therapy (VMAT) and intensity‐modulated proton therapy (IMPT) with robustness using three different proton beam delivery systems with various spot size (σ) ranges: cyclotron‐generated proton beams (CPBs) (σ: 2.7–7.0 mm), linear accelerator proton beams (LPBs) (σ: 2.9–5.5 mm),
Tara Gray   +9 more
wiley   +1 more source

Convergence of energy functionals and stability of lower bounds of Ricci curvature via metric measure foliation [PDF]

open access: yesarXiv, 2018
The notion of the metric measure foliation is introduced by Galaz-Garc\'ia, Kell, Mondino, and Sosa. They studied the relation between a metric measure space with a metric measure foliation and its quotient space. They showed that the curvature-dimension condition and the Cheeger energy functional preserve from a such space to its quotient space.
arxiv  

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