Results 51 to 60 of about 15,914,423 (249)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Journal of Mathematical Analysis and Applications, 2012 The authors discuss the boundedness of Calderón-Zygmund operators on non-homogeneous metric measure spaces. They prove that the boundedness of Calderón-Zygmund operators on \(L^2\) is equivalent to either the boundedness of \(T\) from the atomic Hardy space \(H^1\) to \(L^{1,\infty}\) or from \(H^1\) to \(L^1\) on the measure space \((X,d,\mu)\) in the
Liu, Suile, Yang, Dachun, Yang, Dongyong
openaire +2 more sources
Application of the Fisher-Rao metric to ellipse detection [PDF]
, 2007 The parameter space for the ellipses in a two dimensional image is a five dimensional manifold, where each point of the manifold corresponds to an ellipse in the image. The parameter space becomes a Riemannian manifold under a Fisher-Rao metric, which is
Stephen J. Maybank, Maybank, Stephen J.
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Boundedness of fractional integral operators on non-homogeneous metric measure spaces
, 2013 26 ...
Xie, Rulong, Shu, Lisheng
openaire +2 more sources
Dimension and measure for generic continuous images [PDF]
, 2013 This work is supported by EPSRC Doctoral Training GrantsWe consider the Banach space consisting of continuous functions from an arbitrary uncountable compact metric space, X, into R-n.
James T. Hyde +9 more
core +1 more source
Infinite multidimensional scaling for metric measure spaces [PDF]
, 2022 For a given metric measure space $(X,d,\mu)$ we consider finite samples of points, calculate the matrix of distances between them and then reconstruct the points in some finite-dimensional space using the multidimensional scaling (MDS) algorithm with ...
Trevisan, D. +8 more
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source