Results 111 to 120 of about 120,353 (299)
Animal Models and Experimental Medicine, EarlyView.Irrigation of periodontal pockets with human periopathogens, in combination with a 14‐day ligature‐induced periodontitis protocol, significantly enhances alveolar bone loss and sustains bacterial colonization for up to 28 days following ligature removal, thereby more closely replicating the chronic nature of human periodontitis compared to the ligature
Maksym Skrypnyk +4 more
wiley +1 more source
Citrulline as a Biomarker in the Non-human Primate Total- and Partial-body Irradiation Models
, 2015 Jace W. Jones +8 more
openalex +1 more source
P2‐323: Toll‐like receptor 9 stimulation via CpG ODN in a non‐human primate model of sporadic cerebral amyloid angiopathy [PDF]
, 2015 Henrieta Scholtzova +12 more
openalex +1 more source
Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9
Animal Models and Experimental Medicine, EarlyView.Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu +6 more
wiley +1 more source
Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion
Animal Models and Experimental Medicine, EarlyView.Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams +8 more
wiley +1 more source
Advanced ScienceResearch highlights the significance of increased bursting in lateral habenula (LHb) neurons in depression and as a focal point for bright light treatment (BLT).
Xianwei Liu +10 more
doaj +1 more source
Analysis of beta-cell maturity and mitochondrial morphology in juvenile non-human primates exposed to maternal Western-style diet during development [PDF]
Darian T. Carroll +17 more
openalex +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, EarlyView.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source