Despotism promotes dyadic cooperation through enhanced interdependencies in non-human primate societies. [PDF]
Bhattacharjee D +23 more
europepmc +1 more source
Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis
ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong +6 more
wiley +1 more source
Efficacy of Pam3CSK4 as a cross-species adjuvant for polysaccharide vaccines in humanized mouse and non-human primate models. [PDF]
Jennings-Gee JE, Adams-Sims AE, Haas KM.
europepmc +1 more source
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou +6 more
wiley +1 more source
Hepatitis B Virus in Gabonese Non-Human Primate: Potential Zoonotic Circulation and Long-Term Strain Persistence. [PDF]
Koumba Mavoungou DS +12 more
europepmc +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Neurovascular and inflammatory effects of biperiden in the acute phase of moderate traumatic brain injury: evidence from a non-human primate model. [PDF]
Sanabria V +9 more
europepmc +1 more source
Abstract Evolutionary theory provides a fundamental framework for understanding human anatomy and health. However, evolution acceptance and conceptual understanding are distinct constructs that may not co‐vary. This study aimed to assess (1) evolution acceptance and (2) knowledge of human evolution in health sciences students.
Thomas Colard +4 more
wiley +1 more source
Application of Chorionic Villus Sampling to Longitudinal Studies in Pregnant Non-Human Primate Models. [PDF]
Cilvik SN +6 more
europepmc +1 more source
Abstract Background We conducted a systematic review of clinical trials and cohort studies on HIV post‐exposure prophylaxis (PEP) regimens to inform updated 2025 Canadian guidelines. Methods We searched Medline and Embase (July 2017–June 2024) for studies reporting on: HIV acquisition, PEP completion, adverse events (AEs) leading to discontinuation and/
Stanley O. Onyegbule +12 more
wiley +1 more source

