Results 51 to 60 of about 31,221,148 (284)

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo, Yanxia Zhan, Lili Ji, Pengcheng Xu, Pu Chen, Hao Pang, Yunan Ling, Fanli Hua, Xibing Zhuang, Hao Chen, Yunfeng Cheng   +10 more
wiley   +1 more source

Federated PAC-Bayesian Learning on Non-IID data [PDF]

, 2023
Existing research has either adapted the Probably Approximately Correct (PAC) Bayesian framework for federated learning (FL) or used information-theoretic PAC-Bayesian bounds while introducing their theorems, but few considering the non-IID challenges in
Zhao, Zihao, Liu, Yang, Ding, Wenbo, Zhang, Xiao-Ping   +3 more
core   +1 more source

Dual Randomness From Spatial and Temporal Variations in Stochastic Zinc Gallate Nanoclusters for PUF and TRNG Co‐Driven Image Generation

Advanced Science, EarlyView.
A dual‐randomness hardware platform is demonstrated by integrating PUF and TRNG functionalities into mixed‐ZGO nanoclusters. By leveraging spatial and temporal stochasticity, the mixed‐ZGO NCs device enables both unique identification and random signal generation.
Seungme Kang, Wangmyung Choi, Jueun Lee, Yeong Kwon Kim, Byung Chul Jang, Wonjun Shin, Hocheon Yoo   +6 more
wiley   +1 more source

Interictal Discharge Pattern in Preschool-Aged Children With Tuberous Sclerosis Complex Before and After Resective Epilepsy Surgery

Frontiers in Neurology, 2022
ObjectiveTo analyze the interictal discharge (IID) patterns on pre-operative scalp electroencephalogram (EEG) and compare the changes in IID patterns after removal of epileptogenic tubers in preschool children with tuberous sclerosis complex (TSC ...
Liu Yuan, Liu Yuan, Yangshuo Wang, Shuhua Cheng, Junchen Zhang, Shaohui Zhang, Tinghong Liu, Guojun Zhang, Guojun Zhang, Shuli Liang, Shuli Liang   +10 more
doaj   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

Advanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao, Li Peng, Xiaobin Zheng, Cong Tan, Chuang Wang, Qijiang Xiong, Weiming Chen, Zhao Yang   +7 more
wiley   +1 more source

Federated PAC-Bayesian Learning on Non-IID Data

ICASSP 2024 - 2024 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
Existing research has either adapted the Probably Approximately Correct (PAC) Bayesian framework for federated learning (FL) or used information-theoretic PAC-Bayesian bounds while introducing their theorems, but few considering the non-IID challenges in FL. Our work presents the first non-vacuous federated PAC-Bayesian bound tailored for non-IID local
Zihao Zhao 0001, Yang Liu 0165, Wenbo Ding 0001, Xiao-Ping Zhang 0003   +3 more
openaire   +4 more sources

Farmers' Preferences for Fossil‐Free Mineral Nitrogen Fertilizers: Role of Prices, Climate, Production Origin, and Identity

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Disruptions in global fertilizer markets and climate targets have increased interest in fossil‐free mineral nitrogen fertilizers. This study examines farmers' preferences for conventional (fossil‐based) and fossil‐free fertilizers using a labeled discrete choice experiment with 211 Swedish farmers.
Nasir Adam, Hui Tao, Gordana Manevska‐Tasevska, Per‐Anders Hansson, Vivian Wei Huang, Helena Hansson   +5 more
wiley   +1 more source

The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode [PDF]

, 2003
The sequelae of Infectious Intestinal Disease (IID) in a population-based sample of cases and matched controls were investigated for a period of 3 months following the initial infection.
Rodrigues, L.C., Hudson, M.J., Cowden, JM, Wheeler, JG, Cumberland, P., Rodrigues, LC, Tompkins, D.S., Sethi, D., IID Study Executive, Hudson, MJ, Roderick, PJ, Tompkins, DS, Roderick, P.J., Roberts, JA, Wheeler, J.G., Roberts, J.A., Cumberland, P, Cowden, J.M., Sethi, D   +18 more
core   +1 more source

Consumer Preferences for Craft Beer: The Interplay of Localness and Advertising Language

Agribusiness, EarlyView.
ABSTRACT This study explores the influence of the language of the label, origin of production, and origin of brewing ingredients on Croatian consumers' preferences and willingness to pay for organic craft beer. Employing an online survey and a choice experiment among 223 Croatian alcohol consumers, we find that while there's a willingness to pay a ...
Marija Cerjak, Claudia Bazzani, Andreas C. Drichoutis   +2 more
wiley   +1 more source

Fed-TDA: Federated Tabular Data Augmentation on Non-IID Data

CoRR, 2022
Non-independent and identically distributed (non-IID) data is a key challenge in federated learning (FL), which usually hampers the optimization convergence and the performance of FL. Existing data augmentation methods based on federated generative models or raw data sharing strategies for solving the non-IID problem still suffer from low performance ...
Shaoming Duan, Chuanyi Liu, Peiyi Han, Tianyu He, Yifeng Xu, Qiyuan Deng   +5 more
openaire   +2 more sources