Results 121 to 130 of about 13,509 (257)
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés +2 more
wiley +1 more source
Information Design for Early‐Stage Dose‐Finding Trials
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley +1 more source
Identification of Novel Interacting Proteins of FUZ and GPR161
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar +3 more
wiley +1 more source
ABSTRACT We propose a practical procedure to quantify the time varying influence of parameters on hazard functions for power series compounded lifetime models. The procedure combines likelihood based fitting with a two stage sensitivity analysis and applies to a range of baselines and compounding laws.
Yuancheng Si, Saralees Nadarajah
wiley +1 more source
Age Replacement for Balanced Systems Under Mission Durations
ABSTRACT With advances in technology, systems such as Unmanned Aerial Vehicles (UAV) and planetary landing vehicles whose operation requires maintaining balance across sectors have attracted increasing attention within the balanced systems literature.
Ferhan BAŞ KAMAN
wiley +1 more source
How Does Our Degrading System Perform?
ABSTRACT We discuss the quality of performance of degrading systems when degradation is modeled by a stochastic process with independent increments and increasing sample paths. As an example, the gamma process is considered. First, for the continuously observed degradation, by comparing with the black‐box scenario (without observing degradation), the ...
Maxim Finkelstein +2 more
wiley +1 more source
ABSTRACT Low‐cost sensors are increasingly being used, and also considered for usage in regulatory contexts like air quality monitoring. Proper sensor calibration and uncertainty evaluation is necessary in such cases. With the advance of mobile sensors, for example, installed on top of a car, new test and calibration paradigms are required, in ...
Gertjan Kok, Shahin Tabandeh
wiley +1 more source
Optimal Design of Multiple Moving Average Charts
ABSTRACT The moving average control chart has been used to detect changes in a process mean more quickly than the Shewhart chart. The MA chart takes an unweighted average of the most recent w$w$ values and uses this to make an inference regarding the stability of the process.
Steven E. Rigdon
wiley +1 more source
High‐Dimensional Cumulative Sum Control Charts for Industrial Measurement Systems
ABSTRACT High dimensional sensing in modern factories and energy assets produces thousands of correlated signals. Detecting small process shifts is challenging because many classical multivariate charts lose power or become unstable. We present two cumulative sum procedures for two sample monitoring that remain effective when the number of variables is
Osama Alhadi +3 more
wiley +1 more source
ABSTRACT Electric multiple unit (EMU) trains, widely used in modern railway transportation, use Nickel–Cadmium (Ni–Cd) batteries to power auxiliary systems on board, including lighting, ventilation, control electronics, and emergency systems. These batteries are often connected in parallel to ensure a wider power supply range for electrical loads that ...
Christian Capezza +4 more
wiley +1 more source

