Results 141 to 150 of about 24,187 (251)

Competency‐based European training requirements for the specialty of ophthalmology. Recommendations from the UEMS section of ophthalmology and the European Board of Ophthalmology

Acta Ophthalmologica, Volume 104, Issue 2, Page e204-e215, March 2026.
Abstract Purpose Ophthalmology encompasses comprehensive medical and surgical care for patients with diverse visual system disorders, significantly impacting eye health, vision, and quality of life. European ophthalmologists undergo specialized residency training to acquire necessary competencies, emphasizing theoretical knowledge, clinical and ...
Helena Prior Filipe, Rémi Yaïci, Renata Ivekovic, Denise Curtin, Rimvydas Asoklis, Huban Atilla, Elske Bak, Ana Pueyo‐Bestué, Michèle Beaconsfield, Catherine Creuzot‐Garcher, Barbara Cvenkel, Lisa Flanagan, Saskia Imhof, Tero Kivelä, Carina Koppen, Ewa Mrukwa‐Kominec, Anna Maino, Frédéric Mouriaux, Aurore Muselier, Sorcha Ni Dhubghaill, Karsten Paust, Siegfried Priglinger, Marcin Stopa, Brendan Strong, Felix Tanner, Marie‐José Tassignon, Paul Ursell, The ETR Subspecialties Working Group, Alain Bron, Nicolás Alejandre Alba, Ann Sofia Thomsen, Anthony Kawaja, Augusto Magalhães, Bahram Bodaghi, Béatrice Cochener, Dan Milea, Burkhard Dick, Filomena Ribeiro, Giorgio Porro, Gordana Sunaric Megevand, Hanne Olsen, Helgi Davio Bjornsson, Jelena Potic, Joao Barbosa Breda, Jorge Alió del Barrio, Kanav Khanna, Lauriana Solecki, Léa Dormegny, Léonard Sidhoum, Louis Arnould, Luis Abegão Pinto, Luis Fernandez Vega‐Cueto, Manon Grégoire, Marta Correia, Marta Karhanova, Marie Louise Rasmussen, Michael Stormly Hansen, Miguel Gonzalez‐Andrades, Miguel Lacerda Leitão, Mor Dickman, Neringa Jurkute, Nicole Eter, Oliver Niels Klefter, Rafael Martinez Costa, Santiago Ortiz, Sofia N Androudi, Tiago Monteiro, Thibaud Garcin, Vincent Borderie, Wagih Aclimandos, Tristan Bourcier   +70 more
wiley   +1 more source

Case report: Effectiveness of Janus kinase inhibitors in the management of isolated noninfectious uveitis: a case series

Frontiers in Pharmacology
PurposeThis study aimed to assess the efficacy of Janus kinase inhibitors (JAK-i) in the treatment of refractory isolated non-infectious uveitis.Case presentationWe examined a case series involving three patients with isolated non-infectious uveitis, who
Nina Vidic Krhlikar, Matija Tomšič, Matija Tomšič, Polona Jaki Mekjavić, Polona Jaki Mekjavić, Polona Jaki Mekjavić, Pia Klobučar, Nataša Vidović Valentinčič, Nataša Vidović Valentinčič   +8 more
doaj   +1 more source

New intraocular therapies for non‐infectious uveitis

Acta Ophthalmologica, 2017
SummaryTraditional local treatment of non‐infectious uveitis was limited to steroids with side effects such as cataract and ocular hypertension. Intravitreal (IVT) sirolimus is a novel, non‐steroid, locally delivered mTOR inhibitor under investigation.
openaire   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

Phase 1 Dose Escalation of Single‐Agent Mechlorethamine in Dogs With Lymphoma

Veterinary and Comparative Oncology, Volume 24, Issue 1, Page 51-57, March 2026.
ABSTRACT Mechlorethamine is commonly prescribed to dogs at 3 mg/m2. The minimal toxicity observed indicates that higher doses of mechlorethamine are likely tolerable. The primary objective of this study was to determine the maximally tolerated dose (MTD) of mechlorethamine in dogs with lymphoma.
Laura E. Chadsey, Paul R. Hess, Joanne L. Intile   +2 more
wiley   +1 more source

Cell and Gene Therapy in Equine Ocular Disease

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young, Lauren V. Schnabel, Brian C. Gilger   +2 more
wiley   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

An Atypical Presentation of Tubulointerstitial Nephritis With Uveitis (TINU) in an Older Patient Requiring Emergency Dialysis: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Tubulointerstitial nephritis with uveitis (TINU) is an immune‐mediated systemic disorder most commonly described in adolescents and young adults, and its recognition in older patients remains challenging. We report the case of a 58‐year‐old woman who presented with systemic symptoms and rapidly progressive acute kidney injury.
Yuli Yang, Yangna Shi, Jian Li, Jing Meng, Wenyu Gong   +4 more
wiley   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source